Compare Tradjenta vs. Invokamet
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lowers blood sugar.
Tradjenta (linagliptin) is good add-on medicine for controlling your blood sugar, but may cause body aches.
Lowers blood sugar.
Invokamet (canagliflozin / metformin) is a combination of 2 medicines that can lower your blood sugars, but it still has to be taken twice daily.
Upsides
- Good add-on medicine if your blood sugars are still not controlled
- Good option if you have bad liver or kidney function.
- Can be taken once daily.
- Does not cause weight gain.
- Does not cause hypoglycemia (low blood sugar) when taken by itself.
- Combines 2 effective anti-diabetes medicines into one pill so you don't have to take them separately.
- Does not cause weight gain unlike other anti-diabetic medicines.
- Not as likely to cause hypoglycemia (low blood sugar)
Downsides
- Not first-choice anti-diabetes medicine because it doesn't lower blood sugar levels as much as others.
- Available as brand only and may be expensive
- Not a good option if you have worsening kidney function such as those age 65 years and up.
- May cause increased urination.
- More likely to cause broken bones and yeast and urinary tract infections.
Used for
Dosage forms
- Pill
- Pill
Price
Lowest price
$460.39
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$587.46
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Reviews
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Side effects
6possible side effects
- Back pain9%
- Joint pain8%
- Lung infection8%
- Headache6%
- Cough6%
- Pain in the limbs5%
9possible side effects
- Yeast infection in women11%
- Urinary tract infections6%
- Increased urination5%
- Yeast infection in men4%
- Thirst3%
- Vaginal itching2%
- Constipation2%
- Nausea2%
- Abdominal pain2%
Risks and risk factors
- Inflammation of pancreas (pancreatitis)
- Alcoholism
- Elevated triglycerides
- History of pancreatitis
- Low blood sugar (hypoglycemia)
- Alcoholism
- Exercising more than you usually do
- Insulin
- Other antidiabetic medications
- Severe allergic reactions
- Severe joint pain
- Fluid-filled blisters on the skin (bullous pemphigoid)
- Acid buildup in the blood
- Kidney problems
- Liver problems
- Congestive heart failure
- Contrast dye for procedure
- Surgery
- Alcohol use
- Low blood pressure (hypotension)
- Over age 65
- Kidney problems
- Diuretics
- Taking ACE inhibitors or ARBs
- Low blood pressure
- Bone fractures
- Low blood pressure
- Weak bones (Osteoporosis)
- Kidney damage
- History of kidney damage
- Heart failure
- Blood pressure medicines (water pills, ACE inhibitors, ACE inhibitors)
- Anti-inflammatories (NSAIDs)
- Genital yeast infection and urinary tract infection
- History of urinary tract infections
- History of fungal genital infections
- Uncircumcised males
- Low blood sugars
- Taking other diabetic medications
- Increased exercise
- Drinking alcohol