Compare trifluoperazine vs. Seroquel
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats anxiety and schizophrenia.
Stelazine (trifluoperazine) can be used to treat schizophrenia, but you might have trouble controlling your movements.
Helps control your thoughts and mood.
Seroquel (quetiapine) is a effective at treating schizophrenia, mania, and depression but it can cause weight gain and high blood glucose levels.
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3.7/ 5 average rating with 250 reviewsforSeroquel
Upsides
- Stelazine (trifluoperazine) is one of the recommended medicines for schizophrenia.
- It’s approved in children age 6 and older.
- Available in generic.
- Compared to other similar medicines, you're less likely to feel dehydrated or have problems with your heart with Stelazine (trifluoperazine).
- Seroquel (quetiapine) is effective at relieving psychotic symptoms and manic episodes.
- Seroquel (quetiapine) has fewer side effects than most antipsychotic medications.
- Seroquel (quetiapine) is less likely to cause heart problems compared to some other antipsychotics.
- Seroquel (quetiapine) is also the least likely to cause Extrapyramidal Symptoms (EPS) – a movement disorder that causes stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
Downsides
- If you take Stelazine (trifluoperazine) for more than 12 weeks or are taking high doses of Stelazine (trifluoperazine), you’re at a higher risk for being unable to control your movements.
- Stelazine (trifluoperazine) can cause agitation and trouble sleeping. These symptoms can sometimes disappear, or there are other treatments you can take to help.
- Seroquel (quetiapine) has a moderate to high risk of weight gain, elevated cholesterol and/or blood sugar compared to other antipsychotics.
- You might need routine blood tests to check how Seroquel (quetiapine) is affecting your body.
Used for
Dosage forms
- Pill
- Pill
- Extended release
Price
Lowest price
$23.41
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$13.87
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Reviews
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250 reviews so far
56%
saidit'sworth it
50%
saiditworked well
27%
saidit'sa big hassle
Have you used Seroquel (quetiapine)?
Leave a reviewSide effects
The Stelazine (trifluoperazine) FDA package insert doesn’t have numbers about how common side effects are.
36possible side effects
- Drowsiness34%
- Dry mouth19%
- Headache17%
- Weakness10%
- Constipation10%
- Dizziness9%
- Tremor8%
- Stomach pain7%
- Low blood pressure7%
- Agitation6%
- Weight gain6%
- Sore throat6%
- Back pain5%
- Stiffness/difficulty moving4%
- Hay fever4%
- Swelling in the limbs4%
- Twitching4%
- Indigestion4%
- Depression3%
- Lazy eye3%
- Speech disorder3%
- Altered hormone levels3%
- Heaviness2%
- Infection2%
- Fever2%
- High blood pressure2%
- Increased heart rate2%
- Increased appetite2%
- Hypothyroidism2%
- Incoordination2%
- Abnormal thinking2%
- Anxiety2%
- Loss of control of movements2%
- Sinus infection2%
- Sweating2%
- Urinary Tract Infection2%
Risks and risk factors
- Higher risk of death in people age 65 and older with dementia
- People age 65 and older with dementia and psychosis
- Difficulty controlling movements
- Women age 65 and older
- Neuroleptic malignant syndrome
- Taking antipsychotic medications
- Changes in blood cell counts
- History of low white or red blood cell counts
- Liver damage
- Low blood pressure and higher risk of falls
- Higher risk of death
- Elderly patients with dementia-related psychosis
- Suicidal thoughts or behavior
- Children, adolescents, and young adults (<24 years old)
- Neuroleptic malignant syndrome
- Heart problems
- History of heart problems
- Drug interactions
- Extrapyramidal Symptoms (EPS)
- Metabolic changes (increased blood sugar, high cholesterol and weight gain)
- People with diabetes
- People with high cholesterol