Compare Trileptal vs. Vimpat

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Trileptal (Oxcarbazepine)

Prescription only

Vimpat (lacosamide)

Prescription only
Prevents seizures.

Trileptal (Oxcarbazepine) is effective at preventing seizures and you don’t need to get regular blood tests to make sure it’s effective, but it has many drug interactions.

Controls partial seizures.

Vimpat (lacosamide) is considered a first choice medicine to control partial seizures, but it can be expensive since it's brand name.

Upsides
  • Trileptal (Oxcarbazepine) is effective at lowering the frequency of seizures, especially for people with partial seizures.
  • If you have trouble swallowing tablets, Trileptal (Oxcarbazepine) is also available as an oral solution.
  • You won’t need to get regular blood tests to check the drug levels in your body.
  • Available in a generic form.
  • Vimpat (lacosamide) is part of the first choice medicines to control partial seizures.
  • Available in pills or liquid to use at home, and as an injectable in the hospital.
  • Can be used by itself or with other medicines to control seizures.
  • There are programs available through the manufacturer that can lower your copay.
Downsides
  • It’s important to take your dose on time so that Trileptal (Oxcarbazepine) has steady levels in your body.
  • Interacts with many other medicines and supplements.
  • Can cause difficulty concentrating, tiredness or drowsiness, and problems with coordination.
  • If you have kidney problems, your dose may need to be adjusted. Your doctor will check your kidney function regularly.
  • Being pregnant lowers the levels of Trileptal (Oxcarbazepine), so the medicine might not be as effective at preventing seizures.
  • Only available as a brand name, so it can have a higher copay.
  • There are other medicines similar to Vimpat (lacosamide) that are available as generic and are much cheaper.
  • Vimpat (lacosamide) only works for partial seizures. It can't be used to treat other types of seizures.
  • Vimpat (lacosamide) Is a controlled medicine, so you can only get a limited amount per month.
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Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
  • Liquid
  • Injection
Price
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Reviews
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Side effects
21possible side effects
  • Dizziness
    22%
  • Nausea
    16%
  • Headache
    13%
  • Any adverse effect
    9%
  • Diarrhea
    7%
  • Vomiting
    7%
  • Upper Respiratory Tract Infection
    7%
  • Constipation
    5%
  • Dyspepsia
    5%
  • Ataxia
    5%
  • Nervousness
    5%
  • Falling Down NOS
    4%
  • Pain Back
    4%
  • Amnesia
    4%
  • Coordination Abnormal
    4%
  • Tremor
    4%
  • Epistaxis
    4%
  • Infection Chest
    4%
  • Sinusitis
    4%
  • Rash
    4%
  • Vision Abnormal
    4%
See more detailed side effects
28possible side effects
  • Dizziness
    43%
  • Sleepiness
    26%
  • Nausea
    14%
  • Headache
    13%
  • Fatigue
    12%
  • Double vision
    11%
  • Vomiting
    9%
  • Blurry vision
    8%
  • Difficulty controlling movement
    8%
  • Tremor
    7%
  • Dry mouth
    6%
  • Prickling and tingling sensation
    6%
  • Difficulty controlling eye movements
    5%
  • Prickling and tingling in the mouth
    5%
  • Numbness in the mouth
    5%
  • Loss of balance
    4%
  • Diarrhea
    4%
  • Problems with balance
    4%
  • Itching
    4%
  • Bruising
    3%
  • Skin lacerations
    3%
  • Problems with walking
    3%
  • Chest pain
    3%
  • Problems with coordination
    3%
  • Weakness
    2%
  • Memory problems
    2%
  • Depression
    2%
  • Excessive sweating
    2%
See more detailed side effects
Risks and risk factors
  • Mental changes due to low sodium
    • Age 65 or older
    • dehydration
    • Taking diuretics (water pills)
  • Serious allergic reactions
    • Had allergic reaction to Tegretol (carbamazepine)
  • Life-threatnening skin reactions
    • Asian ancestry
  • Suicidal thoughts or behavior
    • History of depression
  • Withdrawal seizures
    • Stopping Trileptal (Oxcarbazepine) suddenly
  • Changes in blood cells
  • Bone disorders
    • History of osteoporosis
    • History of fractures
  • Liver problems
  • Low thyroid levels
    • Children
See more detailed risks and warnings
  • Suicidal behavior
    • Taking other medicines to control seizures
  • Dizziness and difficulty controlling movements
    • Taking other medicines to control seizures
  • Problems with the heartbeat
    • History of problems with the heartbeat
    • Heart attack
    • Heart failure
    • Heart disease
  • Fainting
    • Taking high doses of Vimpat (lacosamide)
    • Heart disease
    • Taking drugs that slow heart rate
  • Withdrawal seizures
    • Stopping Vimpat (lacosamide) suddenly
  • Severe allergic reactions
See more detailed risks and warnings