Compare Trilipix vs. Lopid

Head-to-head comparisons of medication uses, side effects, ratings, and more.


Lopid (gemfibrozil)

Prescription only
Lowers cholesterol.

Trilipix is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol and cardiovascular disease risk.

2.9/ 5 average rating with 68 reviewsforTrilipix
Lowers cholesterol and triglyceride levels.

Lopid (gemfibrozil) works well to lower triglycerides and bad cholesterol, but it may not be the best option if you're also on a statin drug.

  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Good medicine for lowering triglycerides.
  • Lopid (gemfibrozil) is available as a generic.
  • It can significantly lower your triglycerides and bad cholesterol (LDL), and raise your good cholesterol (HDL).
  • More effective and causes fewer side effects than non-statin cholesterol-lowering medicines.
  • In clinical studies, Trilipix hasn't lowered cholesterol or the risk of heart attack and stroke better than statins.
  • Different forms and strengths of this medication can't be substituted for each other.
  • Since so many people use statin medications to treat their cholesterol, Lopid (gemfibrozil) isn't generally the first choice treatment to use since it can interact with statins.
  • Can be more expensive than some alternative medicines.
  • Need to take Lopid (gemfibrozil) twice a day, whereas other similar medications are only once a day.
Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
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68 reviews so far
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saiditworked well
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Side effects
The Trilipix (Fenofibric Acid) FDA package insert doesn’t have numbers about how common side effects are.
9possible side effects
  • Stomach and intestinal problems
  • Stomach upset
  • Abdominal pain
  • Diarrhea
  • Fatigue
  • Nausea or vomiting
  • Eczema
  • Rash
  • Feeling off balance
See more detailed side effects
Risks and risk factors
  • Muscle pain
    • Taking Trilipix (Fenofibric Acid) with statins
  • Liver damage
    • Past history of liver disease
  • Gallstones
  • Increased bleeding risk
    • Taking Trilipix (Fenofibric Acid) with anticoagulants
  • Pancreatitis
  • Changes in blood tests
  • Skin reactions
  • Blood clots
  • Increased risk for colds and flu
See more detailed risks and warnings
  • Muscle pain
    • Taking Lopid (gemfibrozil) with statins
  • Liver problems
    • Past history of liver disease
  • Kidney problems
    • Kidney problems
  • Bleeding risk
    • Taking Lopid (gemfibrozil) with anticoagulants
  • Breastfeeding
  • Gallstones
See more detailed risks and warnings