Compare Trizivir vs. Baraclude

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Treats HIV infections.

Trizivir (abacavir / lamivudine / zidovudine) is a convenient 3-in-1 medication used to treat HIV infections. It's not a first choice medication, but it can be an option for you if other HIV medications have not controlled your viral load.

Treats hepatitis B.

Baraclude (entecavir) works well to treat hepatitis B, but tenofovir (Viread or Vemlidy) might be the better choice if you’ve taken other oral medicines for hepatitis B before or also have HIV.

  • Trizivir (abacavir / lamivudine / zidovudine) combines three different HIV medications into one tablet.
  • Is available in generic form.
  • Doesn't affect your kidneys or bone density like some other HIV medications.
  • Baraclude (entecavir) is a first-choice medicine to treat hepatitis B.
  • Safer option for people with kidney damage.
  • Side effects are mild and short-lived.
  • Can be used in children as young as 2 years old.
  • Conveniently comes as a liquid for children and people who struggle to swallow pills.
  • Trizivir (abacavir / lamivudine / zidovudine) isn't a first choice medication for treating HIV.
  • Trizivir (abacavir / lamivudine / zidovudine) can increase your risk of heart attack.
  • This is not a great medication to take if you have liver or kidney problems.
  • Severe allergic reactions have happened in some patients taking Trizivir (abacavir / lamivudine / zidovudine). Your doctor will test you for any possible risk of reaction before starting Trizivir (abacavir / lamivudine / zidovudine).
  • Doesn't cure hepatitis B.
  • Might not be a good choice for people who’ve taken Epivir HBV (lamivudine) in the past due to the possibility of resistance.
  • Not the first choice for people with both hepatitis B and HIV.
Used for
  • Hepatitis B
  • Prevention of hepatitis B reinfection after liver transplant
Dosage forms
  • Pill
  • Pill
  • Liquid
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Side effects
13possible side effects
  • Nausea
  • Headache
  • Malaise and fatigue
  • Nausea and vomiting
  • Allergic reaction
  • Diarrhea
  • Fever and/or chills
  • Depressive disorders
  • Musculoskeletal pain
  • Skin rashes
  • Ear/nose/throat infections
  • Viral respiratory infections
  • Anxiety
See more detailed side effects
2possible side effects
  • Headache
  • Tiredness
See more detailed side effects
Risks and risk factors
  • Severe allergic reaction
    • Previous allergic reaction to Trizivir, Triumeq or abacavir
    • Presence of HLA-B*5701 gene
  • Blood and bone marrow problems
    • Advanced HIV
    • Anemia
    • Neutropenia
  • Muscle and kidney damage
    • Extended use of Trizivir (abacavir / lamivudine / zidovudine)
  • Rare, serious condtion
    • Liver disease
    • Women
    • Obesity
  • Worsening hepatitis B infection
    • Hepatitis B Virus infection
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
See more detailed risks and warnings
  • Worsening of hepatitis B infection
    • Stopping Baraclude (entecavir)
  • Hepatitis B and HIV co-infection
    • HIV infection
  • Buildup of acid in the blood and swollen, fatty liver
    • Obesity
    • History of liver disease
    • Women
    • Taking Baraclude (entecavir) for a long time
See more detailed risks and warnings