Compare Trizivir vs. Retrovir

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats HIV infections.

Trizivir (abacavir / lamivudine / zidovudine) is a convenient 3-in-1 medication used to treat HIV infections. It's not a first choice medication, but it can be an option for you if other HIV medications have not controlled your viral load.

Works with other drugs to treat HIV infection or prevents transmission to your baby.

Retrovir (zidovudine) is not the first choice to treat HIV because of its side effects.

Upsides
  • Trizivir (abacavir / lamivudine / zidovudine) combines three different HIV medications into one tablet.
  • Is available in generic form.
  • Doesn't affect your kidneys or bone density like some other HIV medications.
  • Retrovir (zidovudine) is safe and effective for children and infants.
  • Retrovir (zidovudine) is available in several single-pill combination tablets so you don't need to take as many pills.
Downsides
  • Trizivir (abacavir / lamivudine / zidovudine) isn't a first choice medication for treating HIV.
  • Trizivir (abacavir / lamivudine / zidovudine) can increase your risk of heart attack.
  • This is not a great medication to take if you have liver or kidney problems.
  • Severe allergic reactions have happened in some patients taking Trizivir (abacavir / lamivudine / zidovudine). Your doctor will test you for any possible risk of reaction before starting Trizivir (abacavir / lamivudine / zidovudine).
  • Retrovir (zidovudine) can cause serious blood, muscle, and liver problems.
  • Many people experience nausea, vomiting, loss of appetite, and headache when taking Retrovir (zidovudine).
  • Taking Retrovir (zidovudine) can raise your cholesterol and blood sugar levels.
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Used for
  • HIV infection
  • Prevention of mother-to-child HIV transmission
  • HIV Postexposure prophylaxis (PEP)
Dosage forms
  • Pill
  • Pill
  • Liquid
Price
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Reviews
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Side effects
13possible side effects
  • Nausea
    19%
  • Headache
    13%
  • Malaise and fatigue
    12%
  • Nausea and vomiting
    10%
  • Allergic reaction
    8%
  • Diarrhea
    7%
  • Fever and/or chills
    6%
  • Depressive disorders
    6%
  • Musculoskeletal pain
    5%
  • Skin rashes
    5%
  • Ear/nose/throat infections
    5%
  • Viral respiratory infections
    5%
  • Anxiety
    5%
See more detailed side effects
12possible side effects
  • Fever
    25%
  • Cough
    15%
  • Skin rashes
    12%
  • Enlarged liver
    11%
  • Enlarged lymph nodes
    9%
  • Nausea and vomiting
    8%
  • Diarrhea
    8%
  • Nasal discharge or congestion
    8%
  • Wheezing
    7%
  • Pain in the ear
    7%
  • Swelling of the mouth
    6%
  • Enlarged spleen
    5%
See more detailed side effects
Risks and risk factors
  • Severe allergic reaction
    • Previous allergic reaction to Trizivir, Triumeq or abacavir
    • Presence of HLA-B*5701 gene
  • Blood and bone marrow problems
    • Advanced HIV
    • Anemia
    • Neutropenia
  • Muscle and kidney damage
    • Extended use of Trizivir (abacavir / lamivudine / zidovudine)
  • Rare, serious condtion
    • Liver disease
    • Women
    • Obesity
  • Worsening hepatitis B infection
    • Hepatitis B Virus infection
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
See more detailed risks and warnings
  • Blood and bone marrow problems
    • Advanced HIV
    • Anemia
    • Neutropenia
  • Muscle and kidney damage
    • Extended use of Retrovir (zidovudine)
  • Acid build-up in the blood
    • Liver disease
    • Women
    • Obesity
  • Fat redistribution
    • HIV treatment
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
See more detailed risks and warnings