Compare Trulicity vs. Farxiga

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Trulicity (dulaglutide)

Prescription only

Farxiga (dapagliflozin)

Prescription only
Lowers your blood sugar.

Trulicity (dulaglutide) is a once-weekly injectable medicine that's used to control diabetes, but it can be expensive.

Lowers blood sugar.

Farxiga (dapagliflozin) can be used together with other diabetes medicines to help lower your blood sugar, but it can be expensive because it's brand name.

Upsides
  • Lowers A1c (average blood sugar over time) up to 1.5%.
  • May help with weight loss and controling appetite.
  • No limitation for people with kidney problems, but close monitoring is recommended.
  • Dosed once a week compared to other injectables that have to be done daily.
  • Medicine is ready to use, without need to mix.
  • Can lower A1c by 1% (A1c measures your average blood sugar over time.)
  • Can help you lose weight.
  • Less chance of low blood sugar than other diabetes medicines.
Downsides
  • Only available as an injection.
  • Brand name medicine and can be expensive.
  • Many people taking Trulicity (dulaglutide) have upset stomach and side effects like nausea, vomiting, diarrhea, constipation, or indigestion.
  • Not a first choice medicine for diabetes because it doesn't lower blood sugar as much as other medicines.
  • Higher risk of genital yeast infections and urinary tract infections.
  • This is an expensive medication with no generic available at this time.
  • Not shown to improve cardiovascular outcomes like other similar medicines because it can increase cholesterol.
  • Not a good choice if you drink a lot of alcohol.
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Used for
Dosage forms
  • Injection
  • Pill
Price
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Reviews
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Side effects
10possible side effects
  • Low blood sugar
    35%
  • Nausea
    21%
  • Diarrhea
    13%
  • Vomiting
    13%
  • Stomach pain
    9%
  • Low appetite
    9%
  • Indigestion
    6%
  • Tiredness
    6%
  • Constipation
    4%
  • Acid reflux
    2%
See more detailed side effects
13possible side effects
  • Female yeast infection
    8%
  • Common cold symptoms
    7%
  • Urinary tract infection
    6%
  • Back pain
    3%
  • Increased urination
    3%
  • Male yeast infection
    3%
  • Nausea
    3%
  • Flu
    3%
  • Increased cholesterol
    2%
  • Constipation
    2%
  • Discomfort with urination
    2%
  • Pain in hands and feet
    2%
  • Mild low blood sugar
    2%
See more detailed side effects
Risks and risk factors
  • Thyroid cancer
    • History of MTC
    • History of MEN 2
  • inflammation of pancreas (pancreatitis)
    • History of pancreatitis
    • History of gallstones
    • alcoholism
    • Elevated triglycerides
  • Severe allergic reactions
  • Kidney damage
    • Kidney problems
    • dehydration
  • Low blood sugar (hypoglycemia)
    • Use of insulin(s)
    • Use of insulin-secreting medicines.
  • Severe stomach problems
    • Stomach or digestive tract disease
    • Gastroparesis
See more detailed risks and warnings
  • Genital yeast infection
  • Urinary tract infection
  • Low blood pressure
    • Taking water pills for blood pressure
    • Over age 65
    • Kidney problems
  • Kidney problems
    • Kidney damage
    • Taking water pills, ACE inhibitors or ARBs for blood pressure
    • Anti-inflammatory medicines (NSAIDs)
    • Heart failure
  • Increased acid and ketones in the blood
    • Long periods of fasting
    • Alcohol abuse
    • Dehydration
    • History of pancreatitis
See more detailed risks and warnings