Compare Trulicity vs. Janumet

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Lowers your blood sugar.

Trulicity (dulaglutide) is a once-weekly injectable medicine that's used to control diabetes, but it can be expensive.

Lowers your blood sugar.

Janumet is a combination of two anti-diabetic medicines that work better together, but is available as brand only.

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3.4/ 5 average rating with 79 reviewsforJanumet
Upsides
  • Lowers A1c (average blood sugar over time) up to 1.5%.
  • May help with weight loss and controling appetite.
  • No limitation for people with kidney problems, but close monitoring is recommended.
  • Dosed once a week compared to other injectables that have to be done daily.
  • Medicine is ready to use, without need to mix.
  • This 2-in-1 combination can lower the number of pills you have to take daily.
  • Lowers A1c (average blood sugar over time) up to 2.5%.
  • Available in extended and immediate release forms to allow better control of your blood sugar.
  • Doesn't increase your appetite unlike other anti-diabetic medicines.
  • Does not cause hypoglycemia or very low blood sugar.
Downsides
  • Only available as an injection.
  • Brand name medicine and can be expensive.
  • Many people taking Trulicity (dulaglutide) have upset stomach and side effects like nausea, vomiting, diarrhea, constipation, or indigestion.
  • Available as brand name only and may be expensive.
  • Metformin component usually causes upset stomach.
  • Sitagliptin component may increase your risk for throat infections and inflammation of pancreas.
  • Not appropriate for those with poor kidney function.
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Used for
Dosage forms
  • Injection
  • Pill
  • Extended release
Price
Lowest price
$771.44
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Lowest price
$1484.67
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Reviews
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79 reviews so far
46%
saidit'sworth it
38%
saiditworked well
15%
saidit'sa big hassle

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Side effects
10possible side effects
  • Low blood sugar
    35%
  • Nausea
    21%
  • Diarrhea
    13%
  • Vomiting
    13%
  • Stomach pain
    9%
  • Low appetite
    9%
  • Indigestion
    6%
  • Tiredness
    6%
  • Constipation
    4%
  • Acid reflux
    2%
See more detailed side effects
5possible side effects
  • Low blood sugar
    16%
  • Diarrhea
    8%
  • Upper respiratory tract infection
    6%
  • Headache
    6%
  • Abdominal pain
    2%
See more detailed side effects
Risks and risk factors
  • Thyroid cancer
    • History of MTC
    • History of MEN 2
  • inflammation of pancreas (pancreatitis)
    • History of pancreatitis
    • History of gallstones
    • alcoholism
    • Elevated triglycerides
  • Severe allergic reactions
  • Kidney damage
    • Kidney problems
    • dehydration
  • Low blood sugar (hypoglycemia)
    • Use of insulin(s)
    • Use of insulin-secreting medicines.
  • Severe stomach problems
    • Stomach or digestive tract disease
    • Gastroparesis
See more detailed risks and warnings
  • Excess lactic acid in the blood
    • Kidney problems
    • Liver problems
    • Congestive heart failure
    • Using contrast dye for procedures
    • Surgery
    • Alcohol use
  • Low vitamin B12 levels
  • Inflammation of the pancreas
  • Serious allergic reactions
See more detailed risks and warnings
Learn more about Trulicity (dulaglutide)
Learn more about Janumet (sitagliptin / metformin)