Compare Unisom vs. Lunesta
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats allergy symptoms and helps you sleep.
Unisom Sleeptabs (Doxylamine) can help you get a good night's sleep, but you can have a hard time waking up if you don't give yourself enough time to sleep.
●●●●●
3.3/ 5 average rating with 585 reviewsforUnisom
Helps you sleep.
Lunesta (Eszopiclone) is good for falling asleep and staying asleep. Not as habit-forming as some sleep medicines, but more likely to cause withdrawal symptoms if you stop suddenly.
●●●●●
3.3/ 5 average rating with 592 reviewsforLunesta
Upsides
- Works well to help you fall asleep and doesn't make you feel groggy the next morning.
- Has fewer side effects than prescription sleep aid medications.
- Available over the counter without a prescription.
- Not habit-forming like other sleep aids can be.
- Effective at helping people fall asleep faster and sleep longer.
- Not as habit-forming, so you can use it for longer than most other sleep medicines.
Downsides
- Shouldn't be used unless you have a full night to sleep.
- You shouldn't drive after taking Unisom Sleeptabs (Doxylamine) until you know how it affects you.
- Drinking alcohol while taking Unisom Sleeptabs (Doxylamine) isn't recommended.
- It can increase the risk of falls, so elderly people shouldn't use Unisom Sleeptabs (Doxylamine).
- More likely to cause withdrawal symptoms if you stop taking it suddenly.
- Might not be safe if you have a history of drug or alcohol abuse, depression, lung disease, or a condition that affects metabolism.
- It's easy to become reliant on sleep medicines. In the long run, it's better to learn good sleeping habits and behavior so that you can sleep better naturally.
Used for
Dosage forms
- Pill
- Chewable tablet
- Liquid
- Pill
Price
Lowest price
$4.86
Find instant savings near youLowest price
$12.67
Find instant savings near youWant to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
585 reviews so far
58%
saidit'sworth it
32%
saiditworked well
11%
saidit'sa big hassle
Have you used Unisom Sleeptabs (Doxylamine)?
Leave a review592 reviews so far
55%
saidit'sworth it
36%
saiditworked well
17%
saidit'sa big hassle
Have you used Lunesta (Eszopiclone)?
Leave a reviewSide effects
The Unisom Sleeptabs (Doxylamine) FDA package insert doesn’t have numbers about how common side effects are.
10possible side effects
- Headache15%
- Unpleasant Taste8%
- Dyspepsia6%
- Pain4%
- Diarrhea4%
- Pruritus4%
- Dry Mouth3%
- Abnormal Dreams3%
- Neuralgia3%
- Urinary Tract Infection3%
Risks and risk factors
- Overdosage
- Using other drugs with similar ingredients
- Increased side effects
- Age 65 years or older
- Driving impairment
- Taking with alcohol
- Taking other medicines that make you less alert
- Hyperactivity
- Children age 6 years or younger
- Trouble urinating
- Enlarged prostate
- History of bladder problems
- Vision changes
- Glaucoma
- Breastfeeding
- Nursing mothers
- Dependence and withdrawal
- Continuous use for 2 weeks or more
- Driving impairment
- Alcohol
- Taking other medicines that make you less alert
- Less than 7 hours of sleep.
- Abnormal thoughts
- Undiagnosed psychiatric conditions
- Sleep driving
- Taking with alcohol or drugs that acts in the brain
- Serious allergic reactions
- Risk of falls and injury
- Elderly
- Higher dose
- Liver problems
- Taking Lunesta (Eszopiclone) with other nervous system depressants
- Long-term use
- Risk to fetus
- Women of childbearing age
- Breast-feeding