Compare Valium vs. Buspar

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Valium (diazepam)

Prescription only

Buspar (buspirone)

Prescription only
Helps you relax.

Valium (diazepam) is effective for occasional or short-term use for anxiety and muscle spasm. Compared to similar drugs, Valium (diazepam) acts very quickly but can have interactions with other medicines.

3.8/ 5 average rating with 976 reviewsforValium
Helps you relax.

Buspar (buspirone) relieves anxiety with less drowsiness and abuse potential than other anti-anxiety medicines, but it takes time to work and effects might wear off over time.

3.4/ 5 average rating with 67 reviewsforBuspar
Upsides
  • Valium (diazepam) effectively relieves anxiety and muscle spasms.
  • Valium (diazepam) has less severe withdrawal symptoms compared to other similar drugs.
  • Works very quickly.
  • Available in generic.
  • Doesn't cause as much physical dependence or withdrawal symptoms as other medications used for anxiety.
  • Available as a generic, which is cheaper.
  • Tablets can be split for easy dose changes.
  • Doesn't cause as much drowsiness as other medications for anxiety.
Downsides
  • Use of Valium (diazepam) can cause memory problems, drowsiness, dizziness, and confusion.
  • Valium (diazepam) can be habit-forming, so it's not typically used for long-term treatment.
  • Most people find that their body will get used to Valium (diazepam) levels and they may need higher doses over time to achieve the same effect.
  • People with severe liver problems should not take Valium (diazepam). Several drugs can also interfere with how Valium (diazepam) works.
  • Not for quick relief of anxiety symptoms since Buspar (buspirone) can take as long as 4 weeks to fully work.
  • Not as effective for short-term anxiety conditions or panic disorders.
  • Some people find that Buspar (buspirone) loses effectiveness over long periods of time.
  • Must take Buspar (buspirone) twice daily for full effect.
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Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
Price
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Reviews
976 reviews so far
70%
saidit'sworth it
53%
saiditworked well
15%
saidit'sa big hassle

Have you used Valium (diazepam)?

Leave a review
67 reviews so far
46%
saidit'sworth it
45%
saiditworked well
22%
saidit'sa big hassle

Have you used Buspar (buspirone)?

Leave a review
Side effects
The Valium (diazepam) FDA package insert doesn’t have numbers about how common side effects are.
19possible side effects
  • Dizziness
    12%
  • Drowsiness
    10%
  • Nausea
    8%
  • Headache
    6%
  • Nervousness
    5%
  • Fatigue
    4%
  • Trouble sleeping
    3%
  • Lightheadedness
    3%
  • Dry mouth
    3%
  • Worse concentration
    2%
  • Excitement
    2%
  • Anger/hostility
    2%
  • Confusion
    2%
  • Depression
    2%
  • Blurred vision
    2%
  • Upset stomach
    2%
  • Diarrhea
    2%
  • Numbness
    2%
  • Weakness
    2%
See more detailed side effects
Risks and risk factors
  • Decreased breathing from use with opioids
    • Taking Valium (diazepam) with opioids, drugs or alcohol
    • Using Valium (diazepam) for a longer duration and at high doses
  • Dependence and withdrawal
    • History of substance abuse
    • Taking with alcohol or drugs
    • Taking long-term
    • Taking a higher dose
    • Stopping Valium (diazepam) suddenly
  • Driving impairment
    • Alcohol use with Valium (diazepam)
    • Taking other medicines that make you less alert
  • Drug interactions
    • Current liver problems
    • Taking Tagamet, ketoconazole, Prozac, Prilosec
See more detailed risks and warnings
  • Higher blood pressure
    • Taking Buspar (buspirone) with MAOIs
    • Taking Buspar (buspirone) within 14 days after stopping a MAOIs
  • Serotonin syndrome
    • Taking other medicines that affect serotonin levels
  • Withdrawal symptoms from other anti-anxiety medicines
    • Stopping benzodiazepines suddenly
See more detailed risks and warnings