Compare Valium vs. Norflex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Valium (diazepam)

Prescription only

Norflex (orphenadrine)

Prescription only
Helps you relax.

Valium (diazepam) is effective for occasional or short-term use for anxiety and muscle spasm. Compared to similar drugs, Valium (diazepam) acts very quickly but can have interactions with other medicines.

3.8/ 5 average rating with 976 reviewsforValium
Relaxes your muscles.

Norflex (orphenadrine) can be used for relaxing muscle spasms and it also can relieve pain.

Upsides
  • Valium (diazepam) effectively relieves anxiety and muscle spasms.
  • Valium (diazepam) has less severe withdrawal symptoms compared to other similar drugs.
  • Works very quickly.
  • Available in generic.
  • More effective than placebo for treatment of muscle spasms and nonspecific musculoskeletal pain in the short term.
  • Extended release pills last 12 hours.
  • Available as generic.
Downsides
  • Use of Valium (diazepam) can cause memory problems, drowsiness, dizziness, and confusion.
  • Valium (diazepam) can be habit-forming, so it's not typically used for long-term treatment.
  • Most people find that their body will get used to Valium (diazepam) levels and they may need higher doses over time to achieve the same effect.
  • People with severe liver problems should not take Valium (diazepam). Several drugs can also interfere with how Valium (diazepam) works.
  • Not a first choice treatment for muscle spasms.
  • Norflex (orphenadrine) can make you sleepy or drowsy.
  • At higher doses, Norflex (orphenadrine) can make you confused or hallucinate.
  • Dry mouth and difficulty urinating can happen at higher doses.
  • Pills cannot be crushed and must be swallowed whole.
  • Can't be used in people with glaucoma, certain types of bowel obstruction or peptic ulcers, prostatic hypertrophy, certain urinary problems, cardio-spasm (megaesophagus) and myasthenia gravis.
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Used for
Dosage forms
  • Pill
  • Liquid
  • Extended release pill
  • Pill
  • Injection
Price
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Reviews
976 reviews so far
70%
saidit'sworth it
53%
saiditworked well
15%
saidit'sa big hassle

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Side effects
The Valium (diazepam) FDA package insert doesn’t have numbers about how common side effects are.
The Norflex (orphenadrine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Decreased breathing from use with opioids
    • Taking Valium (diazepam) with opioids, drugs or alcohol
    • Using Valium (diazepam) for a longer duration and at high doses
  • Dependence and withdrawal
    • History of substance abuse
    • Taking with alcohol or drugs
    • Taking long-term
    • Taking a higher dose
    • Stopping Valium (diazepam) suddenly
  • Driving impairment
    • Alcohol use with Valium (diazepam)
    • Taking other medicines that make you less alert
  • Drug interactions
    • Current liver problems
    • Taking Tagamet, ketoconazole, Prozac, Prilosec
See more detailed risks and warnings
  • Sleepiness and dizziness
    • Taking other medications that also cause sleepiness
    • Recreational drug use
    • Excessive alcohol use
  • Abuse, dependence and withdrawal
    • Prior history of drug abuse
  • Heart problems
    • History of fast or irregular heartbeat
    • History of heart failure or other heart problems
See more detailed risks and warnings