Compare Velcade vs. bexarotene

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Velcade (bortezomib)

Prescription only

Targretin (bexarotene)

Prescription only
Treats mantle cell lymphoma and multiple myeloma.

Velcade (bortezomib) is a first-choice treatment for multiple myeloma and an effective option for mantle cell lymphoma. However, it frequently causes burning, tingling, and numbness in the hands and feet.

Helps treat skin tumors from T-cell lymphoma.

Targretin (bexarotene) is reserved for when T-cell lymphoma spreads to the skin, but is only used when you haven't responded well enough to other medicines.

Upsides
  • Velcade (bortezomib) improved response and delayed cancer progression in multiple myeloma and mantle cell lymphoma.
  • First-choice treatment for multiple myeloma, and effective treatment for mantle cell lymphoma.
  • Can administer Velcade (bortezomib) on your own at home, after the doctor shows you how.
  • Compared to some other chemotherapy treatments, Velcade (bortezomib) causes less nausea and vomiting.
  • Giving this medicine subcutaneously decreases side effects compared to intravenously.
  • Targretin (bexarotene) can work when other medications have failed.
  • Pill taken once daily.
Downsides
  • Can worsen heart, nerve, and liver conditions.
  • Usually need to take in combination with other cancer medicines.
  • Because of the risk of harm during pregnancy, you need to take use contraception during treatment and for 2 months after treatment ends.
  • People with diabetes will have to check their blood sugar more frequently while taking Velcade (bortezomib).
  • Not a good choice if you're pregnant or planning on getting pregnant.
  • You may need to take other medicines to control your cholesterol and thyroid levels while on Targretin (bexarotene).
  • May lower blood sugar if you're taking diabetes medicines.
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Used for
  • T-cell lymphoma
Dosage forms
  • Injection
  • Pill
Price
No pricing information available
Lowest price
$28483.42
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Reviews
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Side effects
12possible side effects
  • Burning or prickling sensation in limbs
    37%
  • Low platelets
    30%
  • Diarrhea
    28%
  • Nausea
    24%
  • Low white blood cells (neutrophils)
    23%
  • Neuropathic pain
    23%
  • Low red blood cells
    19%
  • Low white blood cells (leukocytes)
    18%
  • Vomiting
    13%
  • Fever
    12%
  • Weakness
    7%
  • Fatigue
    7%
See more detailed side effects
25possible side effects
  • High blood lipids
    79%
  • High cholesterol
    32%
  • Headache
    30%
  • Low thyroid levels
    28%
  • Lack of energy
    20%
  • Rash
    17%
  • Dry skin
    17%
  • Low white blood cells
    17%
  • Nausea
    16%
  • Infection
    13%
  • Swelling in arms and legs
    13%
  • Abdominal pain
    11%
  • Chills
    10%
  • Inflamed, shedding skin
    10%
  • Higher lactic dehydrogenase
    7%
  • Diarrhea
    7%
  • Low red blood cells
    6%
  • Fever
    5%
  • Difficulty sleeping
    5%
  • Flu-like symptoms
    4%
  • Hair loss
    4%
  • Low pale-red blood cells
    4%
  • Vomiting
    4%
  • Back pain
    2%
  • Weight loss
    2%
See more detailed side effects
Risks and risk factors
  • Tingling or numbness in arms or legs
    • Existing peripheral neuropathy (numbness, pain, or burning feeling in feet or hands)
  • Low blood pressure
    • History of fainting
    • Taking medicines that cause low blood pressure
    • Dehydration
  • Heart damage
    • History of heart failure
    • Obesity
    • High cholesterol
    • Diabetes
  • Lung damage
  • Stomach upset
  • Low blood cell counts
See more detailed risks and warnings
  • Harm to unborn baby
    • Sexually active women and men of childbearing age
  • High blood lipids
    • History of high blood lipids
  • Cloudy lenses in the eyes
    • Older age
    • Previous cataracts
  • Liver problems
    • Poor liver function
  • Low thyroid levels
  • Inflammation of the pancreas
    • History of pancreas inflammation
    • High blood lipids
    • Drinking lots of alcohol
    • Current gallbladder problems
    • Taking medicines that raise triglyceride levels
    • Taking other medicines that harm the pancreas
    • Uncontrolled diabetes
See more detailed risks and warnings