Compare Velphoro vs. Fosrenol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lowers phosphate levels.

Velphoro (sucroferric oxyhydroxide) is a great phosphate binder for people with chronic kidney disease on dialysis.

Lowers phosphate levels.

Fosrenol (lanthanum) works well to lower blood phosphate levels without affecting blood calcium levels in people with advanced kidney disease, but it can be expensive, and you need to take it with meals.

  • Similar medications need up to 4 pills per meal to work. You may only need to take 1 tablet of Velphoro (sucroferric oxyhydroxide) per meal.
  • Velphoro (sucroferric oxyhydroxide) tablets taste like berries.
  • Patients find Velphoro (sucroferric oxyhydroxide) as chewable as Tums, and easier to chew than Fosrenol.
  • Works as well as other phosphate binders to lower blood phosphate levels.
  • Easy to take since Fosrenol (lanthanum) comes in powder form, and the tablet form can be crushed or chewed.
  • Is calcium-free, which means Fosrenol (lanthanum) doesn't come with the risk of high calcium levels like some alternative medicines.
  • Velphoro (sucroferric oxyhydroxide) must be taken with meals, so you can't replace a dose that you miss. If you miss a dose, take Velphoro (sucroferric oxyhydroxide) the next time you eat.
  • Velphoro (sucroferric oxyhydroxide) can interact with other medications. Tell your doctor about all the medicines you take, including vitamins and supplements.
  • Like other phosphate binders, Fosrenol (lanthanum) must be taken with meals.
  • Is more expensive than other phosphate binders.
Used for
  • Hyperphosphatemia in end stage renal disease
  • Hyperphosphatemia in advanced kidney disease
Dosage forms
  • Pill
  • Pill
  • Powder
Lowest price
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Side effects
3possible side effects
  • Diarrhea
  • Darkening of stools
  • Nausea
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3possible side effects
  • Nausea
  • Vomiting
  • Stomach pain
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Risks and risk factors
  • Possible high iron risk
    • History of peritonitis
    • History of stomach problems or had major stomach surgery
    • History of liver disease
    • History of iron accumulation
  • Drug interactions
    • Taking levothyroxine
    • Taking doxycycline
See more detailed risks and warnings
  • Blockage of your digestive tract
    • History of changes to your digestive tract's anatomy
    • History of digestive tract problems
    • Taking medicines that can also cause blockage
  • Interference with X-rays
See more detailed risks and warnings