Compare Vemlidy vs. Retrovir

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats hepatitis B virus (HBV) infections.

Vemlidy (tenofovir alafenamide) decreases liver damage from hepatitis B virus (HBV) and has minimal side effects, but doesn't cure the infection.

Works with other drugs to treat HIV infection or prevents transmission to your baby.

Retrovir (zidovudine) is not the first choice to treat HIV because of its side effects.

Upsides
  • Vemlidy (tenofovir alafenamide) is a first-choice medicine to treat hepatitis B.
  • Conveniently taken once daily.
  • Compared to Truvada and Viread (tenofovir disoproxil fumarate), Vemlidy (tenofovir alafenamide) is safer for your kidneys and bones.
  • Retrovir (zidovudine) is safe and effective for children and infants.
  • Retrovir (zidovudine) is available in several single-pill combination tablets so you don't need to take as many pills.
Downsides
  • Might not be the best choice for people with severe kidney damage.
  • There's not enough evidence to show that Vemlidy (tenofovir alafenamide) can be used safely in children ages 18 or younger.
  • Retrovir (zidovudine) can cause serious blood, muscle, and liver problems.
  • Many people experience nausea, vomiting, loss of appetite, and headache when taking Retrovir (zidovudine).
  • Taking Retrovir (zidovudine) can raise your cholesterol and blood sugar levels.
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Used for
  • Hepatitis B treatment
  • HIV infection
  • Prevention of mother-to-child HIV transmission
  • HIV Postexposure prophylaxis (PEP)
Dosage forms
  • Pill
  • Pill
  • Liquid
Price
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Reviews
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Side effects
6possible side effects
  • Headache
    9%
  • Stomach pain
    7%
  • Tiredness
    6%
  • Cough
    6%
  • Nausea
    5%
  • Back pain
    5%
See more detailed side effects
12possible side effects
  • Fever
    25%
  • Cough
    15%
  • Skin rashes
    12%
  • Enlarged liver
    11%
  • Enlarged lymph nodes
    9%
  • Nausea and vomiting
    8%
  • Diarrhea
    8%
  • Nasal discharge or congestion
    8%
  • Wheezing
    7%
  • Pain in the ear
    7%
  • Swelling of the mouth
    6%
  • Enlarged spleen
    5%
See more detailed side effects
Risks and risk factors
  • Worsening of hepatitis B infection
    • Stopping Vemlidy (tenofovir alafenamide)
  • Hepatitis B and HIV co-infection
    • HIV infection
  • Kidney damage
    • Poor kidney function
    • Taking other medicines that can damage the kidneys
  • Buildup of acid in the blood and swollen, fatty liver
  • Lowered bone mineral density
    • Long-term use of Vemlidy (tenofovir alafenamide)
    • Use of other medications that result in loss of electrolytes or minerals
See more detailed risks and warnings
  • Blood and bone marrow problems
    • Advanced HIV
    • Anemia
    • Neutropenia
  • Muscle and kidney damage
    • Extended use of Retrovir (zidovudine)
  • Acid build-up in the blood
    • Liver disease
    • Women
    • Obesity
  • Fat redistribution
    • HIV treatment
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
See more detailed risks and warnings