Compare Vemlidy vs. Videx

Head-to-head comparisons of medication uses, side effects, ratings, and more.


Videx (didanosine)

Prescription only
Treats hepatitis B virus (HBV) infections.

Vemlidy (tenofovir alafenamide) decreases liver damage from hepatitis B virus (HBV) and has minimal side effects, but doesn't cure the infection.

Works with other medicines to treat HIV infection.

Videx (didanosine) is not a first-choice treatment for HIV because there are newer medications that work well and are easier to take. However, Videx (didanosine) can be an option if other HIV medications haven't worked for you.

  • Vemlidy (tenofovir alafenamide) is a first-choice medicine to treat hepatitis B.
  • Conveniently taken once daily.
  • Compared to Truvada and Viread (tenofovir disoproxil fumarate), Vemlidy (tenofovir alafenamide) is safer for your kidneys and bones.
  • Videx (didanosine) is available in pill or liquid form.
  • Videx (didanosine) can be used in children 2 weeks of age and older.
  • Videx (didanosine) can be taken either once or twice daily.
  • Might not be the best choice for people with severe kidney damage.
  • There's not enough evidence to show that Vemlidy (tenofovir alafenamide) can be used safely in children ages 18 or younger.
  • Videx (didanosine) cannot be taken by itself. It must be used with other HIV medications to treat HIV.
  • People commonly experience side effects such as diarrhea, nerve pain, and nausea when taking Videx (didanosine).
  • Videx (didanosine) should be used with caution if you have liver or kidney issues.
  • Videx (didanosine) shouldn't be taken with allopurinol or ribavirin. If you are taking these medicines, let your doctor know.
Used for
  • Hepatitis B treatment
Dosage forms
  • Pill
  • Delayed release Pill
  • Liquid
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Side effects
6possible side effects
  • Headache
  • Stomach pain
  • Tiredness
  • Cough
  • Nausea
  • Back pain
See more detailed side effects
6possible side effects
  • Diarrhea
  • Nerve pain
  • Nausea
  • Headache
  • Rash
  • Vomiting
See more detailed side effects
Risks and risk factors
  • Worsening of hepatitis B infection
    • Stopping Vemlidy (tenofovir alafenamide)
  • Hepatitis B and HIV co-infection
    • HIV infection
  • Kidney damage
    • Poor kidney function
    • Taking other medicines that can damage the kidneys
  • Buildup of acid in the blood and swollen, fatty liver
  • Lowered bone mineral density
    • Long-term use of Vemlidy (tenofovir alafenamide)
    • Use of other medications that result in loss of electrolytes or minerals
See more detailed risks and warnings
  • Pancreatitis
    • History of pancreatic issues
    • Alcohol consumption
    • Concomitant use with Zerit (stavudine)
    • Kidney problems
  • Lactic acidosis & severe liver damage
  • Nerve pain
    • Advanced HIV disease
    • History of peripheral neuropathy
    • Taking other medications that also cause peripheral neuropathy
  • Retinal changes
  • Fat redistribution
    • HIV treatment
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
See more detailed risks and warnings