Compare Vesicare vs. Sanctura

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Vesicare (solifenacin)

Prescription only

Sanctura (trospium)

Prescription only
Treats overactive bladder.

Vesicare (solifenacin) is a good choice for treatment of overactive bladder if exercises and other behavioral methods haven't worked.

Treats overactive bladder.

Sanctura (trospium) is a good treatment for overactive bladder after exercises when other methods to control it haven't worked.

Upsides
  • Vesicare (solifenacin) helps you to urinate less often.
  • Its once daily dosing is more convenient than other medicines that work like it.
  • Sanctura (trospium) is effective at treating overactive bladder.
  • Sanctura (trospium) may be a better choice if you have liver problems.
  • Sanctura (trospium) is available as a generic.
Downsides
  • Can cause drowsiness and increase the risk of falls, especially in the elderly.
  • Not a good option if you have untreated, narrow-angle glaucoma.
  • You have to take Sanctura (trospium) on an empty stomach.
  • You may need to take Sanctura (trospium) twice a day.
  • Sanctura (trospium) can cause drowsiness, dizziness, and increase your risk for falls.
  • Generally not recommended if you older than 65.
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Used for
Dosage forms
  • Pill
  • Pill
  • Extended release
Price
Lowest price
$397.43
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Lowest price
$53.13
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Reviews
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Side effects
8possible side effects
  • Dry mouth
    11%
  • Constipation
    5%
  • Blurry vision
    4%
  • Urinary tract infection
    3%
  • Nausea
    2%
  • Upper abdominal pain
    2%
  • Flu
    2%
  • Dizziness
    2%
See more detailed side effects
4possible side effects
  • Dry mouth
    11%
  • Constipation
    9%
  • Dry eyes
    2%
  • Gas
    2%
See more detailed side effects
Risks and risk factors
  • Tissue swelling
  • Drowsiness
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • People age 65 or older
  • Vision changes
    • Glaucoma
  • Urinary blockage
    • Bladder outflow obstruction
  • Worsening side effects
    • History of kidney problems
    • People age 65 or older
  • Temperature dysregulation
    • Outside in hot weather
    • Dehydrated
    • Exercising
    • Added people 65 and older per Beer's Criteria
    • People age 65 and older
See more detailed risks and warnings
  • Facial swelling & breathing problems
  • Difficulty concentrating
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • People age 65 or older
  • Vision changes
    • Glaucoma
  • Urinary retention
    • Bladder outflow obstruction
  • Increased side effects
    • History of kidney problems
    • People age 65 or older
  • Heat exhaustion
    • Outside in hot weather
    • Dehydrated
    • Exercising
    • People age 65 and older
See more detailed risks and warnings
Learn more about Vesicare (solifenacin)
Learn more about Sanctura (trospium)