Compare Vfend vs. Ambisome

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats fungal infections.

Vfend (voriconazole) is effective at treating many different fungal infections, but it can cause blurry vision and make your eyes more sensitive to light.

Treats fungal infections.

Effective treatment for severe and otherwise, deadly fungal infections.

Upsides
  • Vfend (voriconazole) is good for treating infections caused by many different types of fungi.
  • Available as a generic, and in both tablet and liquid form.
  • Vfend (voriconazole) is the antifungal drug of choice to treat Aspergillosis infection.
  • This is a potentially life-saving medication for serious fungal infections.
  • May cause less side effects and harm to your kidneys compared to the conventional formulation of the drug and Abelcet.
  • Your doctor may be able to give you medicines to prevent or manage any reactions you may have to Ambisome (amphotericin B liposome).
Downsides
  • Vfend (voriconazole) can cause blurry vision and sensitity to bright lights.
  • Vfend (voriconazole) cannot be taken with food.
  • Your skin may become more sensitive to the sun while taking Vfend (voriconazole). Make sure to use sunscreen or wear protective layers.
  • Vfend (voriconazole) has a lot of drug interactions.
  • Vfend (voriconazole) isn't absorbed in the same way by everyone, so you'll probably need to get regular blood tests while taking it.
  • Can only be given as an injection that runs over 1 to 2 hours.
  • Can only be given in a hospital or by trained home health care professional.
  • The entire treatment can range from 1 to 12 weeks, depending on the severity of your infection.
  • Has a lot of side effects like fever, chills, nausea, vomitting, and diarrhea. Your doctor may order regular blood tests to monitor your labs.
  • Your body may have an allergic reaction to the drug or the way it is administered.
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Used for
  • Aspergillosis
  • Candidemia
  • Candidiasis of the esophagus
  • Disseminated candidiasis
  • Mycosis
  • Allergic bronchopulmonary aspergillosis
  • Aspergillosis prophylaxis
  • Blastomycosis
  • Febrile neutropenia
  • Oropharyngeal candidiasis
  • Pulmonary aspergillosis
Dosage forms
  • Pill
  • Liquid
  • Injection
Price
No pricing information available
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Reviews
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Side effects
11possible side effects
  • Abnormal vision
    19%
  • Fever
    6%
  • Nausea
    5%
  • Rash
    5%
  • Chills
    4%
  • Vomiting
    4%
  • Headache
    3%
  • Abnormal liver tests
    3%
  • Sensitivity to light
    2%
  • Fast heart rate
    2%
  • Hallucinations
    2%
See more detailed side effects
44possible side effects
  • Chills
    48%
  • Low potassium
    43%
  • Nausea
    40%
  • Vomiting
    32%
  • Diarrhea
    30%
  • Rash
    25%
  • HIgh glucose
    23%
  • Shortness of breath
    23%
  • Liver labs (alkaline phosphatase) increased
    22%
  • Abnormal kidney function tests (creatinine)
    22%
  • Abnormal kidney function tests (blood urea nitrogen)
    21%
  • Abdominal pain
    20%
  • Low magnesium
    20%
  • Headache
    20%
  • Blood product transfusion reaction
    18%
  • Abnormal liver function (bilirubinemia)
    18%
  • Low calcium
    18%
  • Cough increased
    18%
  • Lung disorder
    18%
  • Insomnia
    17%
  • Abnormal liver enzymes (ALT)
    15%
  • Swelling of the hands and feet
    15%
  • Sudden nose bleeds
    15%
  • Pain
    14%
  • Life-threatening infection
    14%
  • Low blood pressure
    14%
  • Fluid retention
    14%
  • Anxiety
    14%
  • Blood in urine
    14%
  • Weakness
    13%
  • Fast heart rate
    13%
  • Fluid in the lungs
    13%
  • Back pain
    12%
  • Chest pain
    12%
  • Low fluid volume
    12%
  • Infection
    11%
  • Confusion
    11%
  • Runny nose
    11%
  • Itching
    11%
  • Bleeding in the stomach
    9%
  • High blood pressure
    8%
  • Low oxygen in the lungs
    8%
  • Sweating
    7%
  • High sodium
    4%
See more detailed side effects
Risks and risk factors
  • Liver problems
    • Blood disorder
    • Liver disease
  • Abnormal vision or eye sensitivity
  • Abnormal heartbeat
    • QT prolongation
    • Arrhythmia
    • Drugs that cause prolonged QT interval
    • Abnormal electrolytes
  • Gallbladder problems
    • History of gallblader disease
    • People with severe kidney problems
  • Pancreas problems (pancreatitis)
  • Skin reaction to light
    • Children
See more detailed risks and warnings
  • Severe allergic reaction
  • Injection related side effects
  • Kidney injury
    • Preexisting kidney disease
    • Dehydration
  • Low magnesium and potassium
    • Preexisting low magnesium or potassium
  • Changes in blood pressure
See more detailed risks and warnings