Compare Vfend vs. Noxafil

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Vfend (voriconazole)

Prescription only

Noxafil (posaconazole)

Prescription only
Treats fungal infections.

Vfend (voriconazole) is effective at treating many different fungal infections, but it can cause blurry vision and make your eyes more sensitive to light.

Treats and prevents fungal infections.

Noxafil (posaconazole) works against many different fungal infections, but may require close follow-up for potential side effects and drug interactions.

Upsides
  • Vfend (voriconazole) is good for treating infections caused by many different types of fungi.
  • Available as a generic, and in both tablet and liquid form.
  • Vfend (voriconazole) is the antifungal drug of choice to treat Aspergillosis infection.
  • Noxafil (posaconazole) works against more types of fungal infections than other medications like it.
  • Available in liquid form if you have difficulty swallowing pills.
Downsides
  • Vfend (voriconazole) can cause blurry vision and sensitity to bright lights.
  • Vfend (voriconazole) cannot be taken with food.
  • Your skin may become more sensitive to the sun while taking Vfend (voriconazole). Make sure to use sunscreen or wear protective layers.
  • Vfend (voriconazole) has a lot of drug interactions.
  • Vfend (voriconazole) isn't absorbed in the same way by everyone, so you'll probably need to get regular blood tests while taking it.
  • Available as brand version only so may be more expensive than other medications like it.
  • Noxafil (posaconazole) has many drug interactions.
  • The pill and liquid forms are not readily interchangeable without your doctor's help.
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Used for
  • Aspergillosis
  • Candidemia
  • Candidiasis of the esophagus
  • Disseminated candidiasis
  • Mycosis
  • Allergic bronchopulmonary aspergillosis
  • Aspergillosis prophylaxis
  • Blastomycosis
  • Febrile neutropenia
  • Oropharyngeal candidiasis
  • Pulmonary aspergillosis
  • Prevention of fungal infection.
  • Treatment of fungal infection in the mouth or throat
Dosage forms
  • Pill
  • Liquid
  • Extended release pill
  • Liquid
Price
Lowest price
$121.64
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Lowest price
$1435.67
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Reviews
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Side effects
11possible side effects
  • Abnormal vision
    19%
  • Fever
    6%
  • Nausea
    5%
  • Rash
    5%
  • Chills
    4%
  • Vomiting
    4%
  • Headache
    3%
  • Abnormal liver tests
    3%
  • Sensitivity to light
    2%
  • Fast heart rate
    2%
  • Hallucinations
    2%
See more detailed side effects
16possible side effects
  • Diarrhea
    10%
  • Nausea
    9%
  • Headache
    8%
  • Vomiting
    7%
  • Fever
    6%
  • Abdominal pain
    5%
  • Low white blood cells
    4%
  • Fatigue
    3%
  • Herpes simplex
    3%
  • Lung infection
    3%
  • Coughing
    3%
  • Rash
    3%
  • Anorexia
    2%
  • Weakness
    2%
  • Low red blood cells
    2%
  • Increased sweating
    2%
See more detailed side effects
Risks and risk factors
  • Liver problems
    • Blood disorder
    • Liver disease
  • Abnormal vision or eye sensitivity
  • Abnormal heartbeat
    • QT prolongation
    • Arrhythmia
    • Drugs that cause prolonged QT interval
    • Abnormal electrolytes
  • Gallbladder problems
    • History of gallblader disease
    • People with severe kidney problems
  • Pancreas problems (pancreatitis)
  • Skin reaction to light
    • Children
See more detailed risks and warnings
  • Abnormal heartbeat
    • QT prolongation
    • Arrhythmia
    • Drugs that cause prolonged QT interval
    • Abnormal electrolytes
  • Liver problems
    • Blood disorder
    • Liver disease
  • Kidney problems
    • Kidney problems
    • Kidney disease
  • Drug toxicity
See more detailed risks and warnings
Learn more about Vfend (voriconazole)
Learn more about Noxafil (posaconazole)