Compare Videx vs. Zerit

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Works with other medicines to treat HIV infection.

Videx (didanosine) is not a first-choice treatment for HIV because there are newer medications that work well and are easier to take. However, Videx (didanosine) can be an option if other HIV medications haven't worked for you.

Works with other medicines to treat HIV infection.

Within the Nucleoside Reverse Transcriptase Inhibitor (NRTI) drug class, stavudine can be a difficult drug to take. stavudine has numerous serious side effects and probably won't be your first choice.

Upsides
  • Videx (didanosine) is available in pill or liquid form.
  • Videx (didanosine) can be used in children 2 weeks of age and older.
  • Videx (didanosine) can be taken either once or twice daily.
  • stavudine is provided as both capsules and an oral solution.
  • Take with or without food.
  • Can be used by patients on dialysis.
  • While stavudine doesn’t cure HIV, it does reduce the number of viral copies being made in your blood, giving your healthy immune cells (CD4 cells) a better chance to do their job.
Downsides
  • Videx (didanosine) cannot be taken by itself. It must be used with other HIV medications to treat HIV.
  • People commonly experience side effects such as diarrhea, nerve pain, and nausea when taking Videx (didanosine).
  • Videx (didanosine) should be used with caution if you have liver or kidney issues.
  • Videx (didanosine) shouldn't be taken with allopurinol or ribavirin. If you are taking these medicines, let your doctor know.
  • Must take twice a day, every 12 hours.
  • The amount of stavudine you will take is based on your body weight, kidney, and liver function.
  • Interacts with many different medications.
  • May cause serious side effects in your liver, kidneys, and pancreas.
  • Can cause significant tingling in your hands or feet.
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Used for
  • HIV infection
Dosage forms
  • Delayed release Pill
  • Liquid
  • Pill
  • Liquid
Price
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Reviews
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Side effects
6possible side effects
  • Diarrhea
    56%
  • Nerve pain
    25%
  • Nausea
    24%
  • Headache
    22%
  • Rash
    14%
  • Vomiting
    14%
See more detailed side effects
The Zerit (Stavudine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Pancreatitis
    • History of pancreatic issues
    • Alcohol consumption
    • Concomitant use with Zerit (stavudine)
    • Kidney problems
  • Lactic acidosis & severe liver damage
  • Nerve pain
    • Advanced HIV disease
    • History of peripheral neuropathy
    • Taking other medications that also cause peripheral neuropathy
  • Retinal changes
  • Fat redistribution
    • HIV treatment
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
See more detailed risks and warnings
  • Lactic acidosis
  • Pancreatitis
  • Liver damage
    • Use of hydroxyurea, didanosine, and stavudine together
  • Peripheral neuropathy
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
  • Fat Redistribution
    • HIV treatment
See more detailed risks and warnings