Compare Viekira Pak vs. Viekira XR

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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A combination of 4 different medications that treats hepatitis C infection.

Viekira Pak (ombitasvir, paritaprevir, ritonavir, and dasabuvir) is a drug regimen consisting of four pills; it's effective against genotype 1 hepatitis C virus, but may not be the best option if you have severe liver problems.

A combination of 3 different medicines that treats hepatitis C infection.

Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) is a once daily drug regimen consisting of 3 pills a day that are effective against genotype 1 hepatitis C virus, but may not be a good option if you have liver problems.

Upsides
  • Viekira Pak (ombitasvir, paritaprevir, ritonavir, and dasabuvir) effectively treats 95% to 100% of people with genotype 1 Hepatitis C.
  • The common side effects are manageable and include feeling nauseous, tired, itching or rash.
  • Viekira Pak (ombitasvir, paritaprevir, ritonavir, and dasabuvir) can also be used to treat genotype 1 hepatitis C if you have a liver transplant.
  • Unlike Viekira Pak, Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) is only three pills that is taken all at once.
  • Similar to Viekira Pak, Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) has a 95% to 100% cure rate.
  • Common side effects are manageable and include feeling nauseous, tired, itching, or rash.
  • Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) can also be used to treat genotype 1 hepatitis C if you have a liver transplant.
Downsides
  • Viekira Pak (ombitasvir, paritaprevir, ritonavir, and dasabuvir) can only treat genotype 1 hepatitis C and must be taken twice a day.
  • You might have to take to take Viekira Pak (ombitasvir, paritaprevir, ritonavir, and dasabuvir) with an additional medication called ribavirin. This may not be a good option if you are uncomfortable swallowing pills.
  • If you take medications containing ethinyl estradiol (an estrogen), you will need another form of birth control during and for 2 weeks after using Viekira Pak (ombitasvir, paritaprevir, ritonavir, and dasabuvir).
  • Should not be used if you experienced severe rash after taking ritonavir (Norvir).
  • Your doctor will need to take frequent blood tests during the first 4 weeks and periodically after to monitor your liver function.
  • Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) is a combination of 3 different medications which may be hard to take if you don't like swallowing a lot of pills.
  • You may need to take an additional medication called ribavirin with Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir).
  • If you are taking ethinyl estradiol-containing medications, you will need another form of birth control during and for 2 weeks after using Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir).
  • Should not be used if you experienced severe rash after taking ritonavir (Norvir).
  • Your doctor will need to take frequent blood tests during the first 4 weeks, and periodically after to monitor your liver function.
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Used for
  • Hepatitis C infection genotype 1
  • Hepatitis C infection genotype 1
Dosage forms
  • Pill
  • Pill
Price
Lowest price
$27403.70
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Reviews
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Side effects
4possible side effects
  • Nausea
    16%
  • Itching
    13%
  • Trouble sleeping
    12%
  • Weakness/Lack of energy
    9%
See more detailed side effects
6possible side effects
  • Fatigue
    34%
  • Nausea
    22%
  • Itching
    18%
  • Skin reactions
    16%
  • Trouble sleeping
    14%
  • Weakness/Lack of energy
    14%
See more detailed side effects
Risks and risk factors
  • Hepatitis B reactivation
    • Hepatitis B infection
  • Serious liver problems and complications
    • Moderate to severe liver disease (Child Pugh B or C)
  • Raised liver blood tests
    • Taking estrogen containing medications
  • Ribavirin warnings
  • Drug interactions
See more detailed risks and warnings
  • Hepatitis B reactivation
    • Hepatitis B infection
  • Serious liver problems and complications
    • Moderate to severe liver disease (Child Pugh B or C)
  • Raised liver blood tests
    • Taking estrogen containing medications
  • Ribavirin warnings
  • Drug interactions
  • HIV resistance
    • HIV infection
See more detailed risks and warnings