Compare Viekira XR vs. Copegus

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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A combination of 3 different medicines that treats hepatitis C infection.

Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) is a once daily drug regimen consisting of 3 pills a day that are effective against genotype 1 hepatitis C virus, but may not be a good option if you have liver problems.

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Upsides
  • Unlike Viekira Pak, Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) is only three pills that is taken all at once.
  • Similar to Viekira Pak, Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) has a 95% to 100% cure rate.
  • Common side effects are manageable and include feeling nauseous, tired, itching, or rash.
  • Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) can also be used to treat genotype 1 hepatitis C if you have a liver transplant.
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Downsides
  • Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir) is a combination of 3 different medications which may be hard to take if you don't like swallowing a lot of pills.
  • You may need to take an additional medication called ribavirin with Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir).
  • If you are taking ethinyl estradiol-containing medications, you will need another form of birth control during and for 2 weeks after using Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir).
  • Should not be used if you experienced severe rash after taking ritonavir (Norvir).
  • Your doctor will need to take frequent blood tests during the first 4 weeks, and periodically after to monitor your liver function.
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Used for
  • Hepatitis C infection genotype 1
  • Hematopoietic stem cell transplant - Respiratory syncytial virus infection Hepatitis C
  • Chronic
  • Combination therapy in interferon alfa-naive patients with compensated liver disease - HIV infection Hepatitis C
  • Chronic
  • With compensated liver disease Respiratory syncytial virus infection
  • Herpes simplex Influenza Viral hemorrhagic fever
Dosage forms
  • Pill
  • Pill
  • Liquid
  • Inhaler
No pricing information available
No pricing information available
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Reviews
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Side effects
6possible side effects
  • Fatigue
    34%
  • Nausea
    22%
  • Itching
    18%
  • Skin reactions
    16%
  • Trouble sleeping
    14%
  • Weakness/Lack of energy
    14%
See more detailed side effects
The Copegus (Ribavirin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Hepatitis B reactivation
    • Hepatitis B infection
  • Serious liver problems and complications
    • Moderate to severe liver disease (Child Pugh B or C)
  • Raised liver blood tests
    • Taking estrogen containing medications
  • Ribavirin warnings
  • Drug interactions
  • HIV resistance
    • HIV infection
See more detailed risks and warnings
No information currently available
Learn more about Viekira XR (ombitasvir, paritaprevir, ritonavir, and dasabuvir)
Learn more about Copegus (Ribavirin)