Compare Vigamox vs. Zylet

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats eye infections.

Vigamox (moxifloxacin) is effective at treating eye infections, but it can be expensive.

Treats certain eye inflammation and infections.

Zylet (loteprednol and tobramycin) is a good choice for certain eye infections and conditions, but isn't for everyone and you can't use it for a long time.

Upsides
  • Infection may start to feel better and clear up on days 5-6.
  • Because it works directly on the eye, you won't get the same side effects (like diarrhea) from taking the pill form.
  • Zylet (loteprednol and tobramycin) is very effective at reducing inflammation and treating infection in certain eye conditions.
  • Since Zylet (loteprednol and tobramycin) is applied directly into the eye, you won't experience any severe body side effects.
Downsides
  • May need to use Vigamox (moxifloxacin) multiple times a day, which can be inconvenient.
  • Not available as a generic eye drop medication.
  • Common side effects include eye irritation, eye pain, dry eyes, and teary eyes.
  • Zylet (loteprednol and tobramycin) is expensive.
  • Taking Zylet (loteprednol and tobramycin) can be burdensome, as you have to use it multiple times a day.
  • There's a limit to how much Zylet (loteprednol and tobramycin) can be used.
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Used for
  • Steroid responsive eye inflammation conditions
  • Superficial eye infections
  • Blepharitis
Dosage forms
  • Eye drops
  • Eye drops
Price
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Reviews
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Side effects
6possible side effects
  • Pinkeye
    6%
  • Decreased visual acuity
    6%
  • Dry eyes
    6%
  • Eye irritation
    6%
  • Eye pain
    6%
  • Itchy eyes
    6%
See more detailed side effects
12possible side effects
  • Headache
    14%
  • Increased eye pressures
    10%
  • Eye burning
    9%
  • Eye stinging
    9%
  • Vision problems
    4%
  • Eye discharge
    4%
  • Eye itching
    4%
  • Tearing problems
    4%
  • Light sensitivity
    4%
  • Eye deposits
    4%
  • Eyelid problems
    4%
  • Other non-specific eye disorders
    4%
See more detailed side effects
Risks and risk factors
  • Superinfection
  • Avoidance of contact lens wear
See more detailed risks and warnings
  • Increased eye pressure
    • Taking Zylet (loteprednol and tobramycin) with other steroids
  • Cataracts
  • Delayed healing
    • Recent cataract surgery
    • Cornea problems
  • Second infections
    • Acute purulent eye infections
  • Allergic reaction
See more detailed risks and warnings