Compare Viread vs. Trizivir

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Works with other medicines to treat HIV infection. Also treats Hepatitis B Virus.

Viread (tenofovir) is a first-line choice to be used in combination with other medications to treat HIV. Viread (tenofovir) is also a first-line choice in treating HBV.

Treats HIV infections.

Trizivir (abacavir / lamivudine / zidovudine) is a convenient 3-in-1 medication used to treat HIV infections. It's not a first choice medication, but it can be an option for you if other HIV medications have not controlled your viral load.

  • Can be used with other medications to prevent HIV infection after an exposure.
  • Taken only once daily, with or without food.
  • There are newer formulations of Viread (tenofovir) available that are safer on your kidneys.
  • If tablets are hard for you to swallow, Viread (tenofovir) is available in a powder that's mixed with soft foods.
  • Trizivir (abacavir / lamivudine / zidovudine) combines three different HIV medications into one tablet.
  • Is available in generic form.
  • Doesn't affect your kidneys or bone density like some other HIV medications.
  • Viread (tenofovir) can't be used on its own to treat HIV infection.
  • Not recommended for patients with kidney damage.
  • Can weaken your bones.
  • Might worsen hepatitis B infections if you suddenly stop taking it.
  • Trizivir (abacavir / lamivudine / zidovudine) isn't a first choice medication for treating HIV.
  • Trizivir (abacavir / lamivudine / zidovudine) can increase your risk of heart attack.
  • This is not a great medication to take if you have liver or kidney problems.
  • Severe allergic reactions have happened in some patients taking Trizivir (abacavir / lamivudine / zidovudine). Your doctor will test you for any possible risk of reaction before starting Trizivir (abacavir / lamivudine / zidovudine).
Used for
Dosage forms
  • Pill
  • Powder
  • Pill
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Side effects
1possible side effects
  • Nausea
See more detailed side effects
13possible side effects
  • Nausea
  • Headache
  • Malaise and fatigue
  • Nausea and vomiting
  • Allergic reaction
  • Diarrhea
  • Fever and/or chills
  • Depressive disorders
  • Musculoskeletal pain
  • Skin rashes
  • Ear/nose/throat infections
  • Viral respiratory infections
  • Anxiety
See more detailed side effects
Risks and risk factors
  • Lactic acidosis | Enlarged, fatty liver
    • Liver disease
    • Women
    • Obesity
  • Cannot be used to treat Hepatitis B Virus (HBV)
    • Hepatitis B Virus infection
  • Mood and behavior changes
    • History of mental illness
  • Decreased bone mineral density
    • History of bone fractures
    • Osteoporosis
  • Kidney damage
    • History of kidney damage
    • Concurrent use of other drugs known to harm kidneys
  • Hypersensitivity (allergic) reactions
    • Prior severe allergic reaction to Viread (tenofovir) or any of its individual drug components.
See more detailed risks and warnings
  • Severe allergic reaction
    • Previous allergic reaction to Trizivir, Triumeq or abacavir
    • Presence of HLA-B*5701 gene
  • Blood and bone marrow problems
    • Advanced HIV
    • Anemia
    • Neutropenia
  • Muscle and kidney damage
    • Extended use of Trizivir (abacavir / lamivudine / zidovudine)
  • Rare, serious condtion
    • Liver disease
    • Women
    • Obesity
  • Worsening hepatitis B infection
    • Hepatitis B Virus infection
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
See more detailed risks and warnings