Compare Vytorin vs. Crestor
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lowers cholesterol.
Vytorin is expensive and is no more effective than simvastatin by itself.
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3.3/ 5 average rating with 99 reviewsforVytorin
Lowers cholesterol.
Crestor (rosuvastatin) is one of the most effective statins to improve cholesterol. It's also available as a generic.
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3.7/ 5 average rating with 751 reviewsforCrestor
Upsides
- A 2-in-1 cholesterol-lowering combination medicine.
- Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
- It's a good first choice medicine for lowering cholesterol levels when diet and exercise aren't enough.
- Slows down the buildup of fatty deposits in your blood vessels, otherwise known as a hardening of the arteries.
- In clinical studies, Crestor (rosuvastatin) has the strongest effect on lowering "bad" cholesterol compared to other statins.
- Can lower your risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
- Available as a generic drug.
Downsides
- In clinical studies, simvastatin/ezetimibe hasn't controlled cholesterol better than simvastatin alone.
- There's no generic available, so it can be expensive.
- You're more likely to have side effects if you're a female, are 65 years or older, drink alcohol every day, or take more than one medicine for cholesterol.
- People with liver disease, kidney disease, or diabetes are also more likely to have side effects from Crestor (rosuvastatin).
- Crestor (rosuvastatin) isn't safe to use if you're pregnant since it can hurt the fetus.
Used for
- High cholesterol
- High triglycerides
- Heart protection
- Atherosclerosis
- Hereditary hypercholesterolemia
- Post-heart attack treatment
Dosage forms
- Pill
- Pill
Price
Lowest price
$64.70
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$10.15
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Reviews
99 reviews so far
53%
saidit'sworth it
36%
saiditworked well
19%
saidit'sa big hassle
Have you used Vytorin (Ezetimibe / Simvastatin)?
Leave a review751 reviews so far
60%
saidit'sworth it
47%
saiditworked well
15%
saidit'sa big hassle
Have you used Crestor (rosuvastatin)?
Leave a reviewSide effects
8possible side effects
- Headache6%
- Any side effect5%
- Increased ALT4%
- Myalgia4%
- Upper respiratory tract infection4%
- Diarrhea3%
- Influenza2%
- Pain in extremity2%
The Crestor (rosuvastatin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Muscle pain
- Asian patients taking high-dose niacin
- Liver damage
- Past history of liver disease
- heavy alcohol use
- High blood sugar
- Diabetes
- Increased risk for colds and flu
- Skin reactions
- Harm to fetus
- Pregnancy
- Elevated INR
- Taking Coumadin (warfarin)
- Muscle pain
- Age 65 or older
- Taking higher doses of Crestor (rosuvastatin)
- Increased blood sugars
- Diabetes
- Liver damage
- Heavy alcohol use
- Prior history of chronic liver disease
- Birth defects
- Pregnancy