Compare Vytorin vs. Lopid

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Lowers cholesterol.

Vytorin is expensive and is no more effective than simvastatin by itself.

3.3/ 5 average rating with 99 reviewsforVytorin
Lowers cholesterol and triglyceride levels.

Lopid (gemfibrozil) works well to lower triglycerides and bad cholesterol, but it may not be the best option if you're also on a statin drug.

Upsides
  • A 2-in-1 cholesterol-lowering combination medicine.
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Lopid (gemfibrozil) is available as a generic.
  • It can significantly lower your triglycerides and bad cholesterol (LDL), and raise your good cholesterol (HDL).
  • More effective and causes fewer side effects than non-statin cholesterol-lowering medicines.
Downsides
  • In clinical studies, simvastatin/ezetimibe hasn't controlled cholesterol better than simvastatin alone.
  • There's no generic available, so it can be expensive.
  • Since so many people use statin medications to treat their cholesterol, Lopid (gemfibrozil) isn't generally the first choice treatment to use since it can interact with statins.
  • Can be more expensive than some alternative medicines.
  • Need to take Lopid (gemfibrozil) twice a day, whereas other similar medications are only once a day.
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Used for
Dosage forms
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Price
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Reviews
99 reviews so far
53%
saidit'sworth it
36%
saiditworked well
19%
saidit'sa big hassle

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Side effects
8possible side effects
  • Headache
    6%
  • Any side effect
    5%
  • Increased ALT
    4%
  • Myalgia
    4%
  • Upper respiratory tract infection
    4%
  • Diarrhea
    3%
  • Influenza
    2%
  • Pain in extremity
    2%
See more detailed side effects
9possible side effects
  • Stomach and intestinal problems
    34%
  • Stomach upset
    20%
  • Abdominal pain
    10%
  • Diarrhea
    7%
  • Fatigue
    4%
  • Nausea or vomiting
    3%
  • Eczema
    2%
  • Rash
    2%
  • Feeling off balance
    2%
See more detailed side effects
Risks and risk factors
  • Muscle pain
    • Asian patients taking high-dose niacin
  • Liver damage
    • Past history of liver disease
    • heavy alcohol use
  • High blood sugar
    • Diabetes
  • Increased risk for colds and flu
  • Skin reactions
  • Harm to fetus
    • Pregnancy
See more detailed risks and warnings
  • Muscle pain
    • Taking Lopid (gemfibrozil) with statins
  • Liver problems
    • Past history of liver disease
  • Kidney problems
    • Kidney problems
  • Bleeding risk
    • Taking Lopid (gemfibrozil) with anticoagulants
  • Breastfeeding
  • Gallstones
See more detailed risks and warnings