Compare Wellbutrin vs. Oleptro
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Improves mood.
Wellbutrin (Bupropion) is good for treating depression and has fewer sexual side effects than other antidepressants, but you need to be okay with avoiding alcohol.
●●●●●
3.4/ 5 average rating with 1164 reviewsforWellbutrin
Improves mood and helps you sleep.
Oleptro (Trazodone) works well as a sleep aid, but has more side effects when used at higher doses for treating depression.
●●●●●
3.6/ 5 average rating with 59 reviewsforOleptro
Upsides
- Effective at relieving depression symptoms.
- Causes fewer sexual side effects than other antidepressants. Can actually boost sex drive for some people.
- Can be taken with other antidepressants to counteract their sexual side effects.
- Has some stimulant effects, so it can be energizing.
- Can help with ADHD symptoms.
- Also used to suppress appetite and help you quit smoking.
- Six out of ten people who use an antidepressant for the first time find that it works for them.
- Commonly used in lower doses to help treat sleep problems (insomnia).
- Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
- Fewer sexual side effects than many other antidepressants.
- Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
- Comes as a generic medication and is cheaper than many other sleep aides.
- Six out of ten people who use an antidepressant for the first time find that it works for them.
Downsides
- Wellbutrin (Bupropion) can be stimulating, so it can cause anxiety or insomnia the first few days you're taking it.
- Generally not as good as other antidepressants for people who have anxiety.
- It's less likely to cause weight gain than other antidepressants.
- Has a higher risk of causing seizures, especially if you have a seizure disorder, eating disorder, or if you drink alcohol. So, it's not a good medication if you drink a lot.
- It contains the same ingredient as a medication that helps you to stop smoking, (Zyban), so these two meds can't be used together.
- Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24.
- The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
- Not as effective as other medications for depression.
- More sedating than other antidepressants.
- Causes more side effects when used at higher doses for depression. Includes sleepiness, dizziness, upset stomach, and irregular heartbeat.
- Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
- The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
Used for
- Depression
- Seasonal affective disorder prevention
- Smoking cessation
- Bipolar disorder
- Sexual dysfunction from taking SSRI antidepressant
Dosage forms
- Pill
- Extended release
- Pill
- Extended release
Price
Lowest price
$10.30
Find instant savings near youLowest price
$4.00
Find instant savings near youWant to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
1164 reviews so far
60%
saidit'sworth it
40%
saiditworked well
13%
saidit'sa big hassle
Have you used Wellbutrin (Bupropion)?
Leave a review59 reviews so far
73%
saidit'sworth it
49%
saiditworked well
24%
saidit'sa big hassle
Have you used Oleptro (Trazodone)?
Leave a reviewSide effects
29possible side effects
- Agitation32%
- Dry mouth28%
- Constipation26%
- Headache/migraine26%
- Nausea/vomiting23%
- Dizziness22%
- Excessive sweating22%
- Tremor21%
- Sleepiness20%
- Insomnia19%
- Blurred vision15%
- Tachycardia11%
- Confusion8%
- Rash8%
- Hostility6%
- Auditory disturbance5%
- Menstrual complaints5%
- Cardiac arrhythmias5%
- Impaired sleep quality4%
- Sensory disturbance4%
- Appetite increase4%
- Palpitations4%
- Hypertension4%
- Impotence3%
- Anxiety3%
- Decreased libido3%
- Gustatory disturbance3%
- Dyspepsia3%
- Hypotension3%
29possible side effects
- Somnolence/Sedation46%
- Drowsiness41%
- Dry Mouth34%
- Headache33%
- Dizziness/Lightheadedness28%
- Dry mouth25%
- Dizziness25%
- Nausea21%
- Blurred Vision15%
- Fatigue15%
- Nausea/Vomiting13%
- Diarrhea9%
- Constipation8%
- Skin Condition/Edema7%
- Weight Loss6%
- Nasal/Sinus Congestion6%
- Abdominal/Gastric Disorder6%
- Syncope5%
- Musculoskeletal Aches/Pains5%
- Tremors5%
- Nightmares/Vivid Dreams5%
- Weight Gain5%
- Back pain5%
- Vision blurred5%
- Sexual dysfunction5%
- Hypotension4%
- Incoordination2%
- Ejaculation disorders2%
- Decreased libido2%
Risks and risk factors
- Suicidal thoughts or behavior
- Age 24 years or younger
- Psychiatric effects for smoking cessation
- History of depression
- History of bipolar disorder
- At risk for bipolar disorder
- Withdrawing from nicotine
- Seizures
- History of seizures
- Alcoholism
- Eating disorder
- Higher dose
- Drug interactions
- Mania
- History of bipolar disorder
- At risk for bipolar disorder
- Increased side effects
- Current kidney problems
- Current liver problems
- Weight loss
- Suicidal thoughts or behavior
- Age 24 years or younger
- Seizures
- History of seizures
- Alcoholism
- Eating disorder
- Higher dose
- Drug interactions
- Painful erection
- Low blood pressure
- Age 65 years or older
- Driving impairment
- Alcohol
- Taking other medicines that make you less alert