Compare Xalatan vs. pilocarpine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Xalatan (Latanoprost)

Prescription only
Lowers eye pressure.

Xalatan (Latanoprost) lowers high pressure in the eye well and helps prevent glaucoma.

Lowers eye pressure and constricts the pupil.

Isopto Carpine (pilocarpine) is a very effective first choice medicine for treating high eye pressure to prevent the onset or worsening of glaucoma, but you may have to use up to 4 times daily.

Upsides
  • It's easy to use and you only need to give yourself one drop each day in the evening.
  • Can be used along with other eye drops, if needed for better results.
  • Xalatan (Latanoprost) is available generically.
  • Xalatan (Latanoprost) can increase the length, thickness, and number of your eyelashes.
  • It takes about 1 hour for Isopto Carpine (pilocarpine) to lower dangerously high eye pressure.
  • It does not require dose adjustments in patients with liver or kidney problems.
  • Available as a generic.
Downsides
  • Xalatan (Latanoprost) can turn the colored part of your eye and your eyelashes brown.
  • Isopto Carpine (pilocarpine) causes the pupil of the eye to become smaller, which results in dim vision, particularly at night.
  • Alternatives are easier to use than this medication, since it requires more drops throughout the day.
  • Isopto Carpine (pilocarpine) is a recommended choice, but it may not work for more serious conditions.
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Used for
Dosage forms
  • Eye drops
  • Eye drops
Price
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Reviews
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Side effects
The Xalatan (Latanoprost) FDA package insert doesn’t have numbers about how common side effects are.
The Isopto Carpine (pilocarpine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Darkening of lenses
    • Replacing contact lenses to soon
  • Darkening of lashes
    • Long term use
See more detailed risks and warnings
  • Reduced visual acuity
  • Retinal disease
    • Retinal disease
  • Increased intraocular pressure in children
    • Use of Isopto Carpine (pilocarpine) in pediatric patients
See more detailed risks and warnings