Compare Xarelto vs. Savaysa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

ADVERTISEMENT

Xarelto (rivaroxaban)

Prescription only

Savaysa (edoxaban)

Prescription only
Prevents blood clots.

Xarelto (rivaroxaban) is a good medication for preventing blood clots. It doesn't require regular blood tests or changing doses often. However, it can be expensive and there's no way to reverse the medication's effects.

3.5/ 5 average rating with 22 reviewsforXarelto
Prevents blood clots.

Savaysa (edoxaban) can prevent blood clots without food restrictions or frequent blood tests. However, its effects will be hard to reverse in the event of an overdose.

Upsides
  • Studies show that Xarelto (rivaroxaban) works just as well as other blood thinners (anticoagulants) in preventing strokes and stopping clots from froming.
  • Xarelto (rivaroxaban) doesn't require regular blood tests or frequent dose changes.
  • Xarelto (rivaroxaban) doesn't interact with as many types of food as other blood thinners like warfarin (Coumadin).
  • Works as well as other blood thinners to prevent strokes or blood clots.
  • Does not require frequent blood tests like warfarin.
  • Does not require food restrictions like warfarin.
Downsides
  • Xarelto (rivaroxaban) can increase your risk of bleeding, so call your doctor right away if you see blood in your spit, urine, or stool (look for black, tarry stools or bright red blood).
  • Xarelto (rivaroxaban) isn't available as a generic medication.
  • There are no antidotes to stop bleeding caused by taking too much Xarelto (rivaroxaban).
  • You can't take Xarelto (rivaroxaban) if you are pregnant.
  • Taking Savaysa (edoxaban) raises your risk of bleeding and bruising. If you take Savaysa (edoxaban) along with other anti-inflammatory medicines like aspirin or ibuprofen, this can make you even more likely to bleed and bruise easily.
  • Savaysa (edoxaban) is not available as a generic medicine so it can be quite pricey.
  • You may not be able to concentrate enough drug in your blood if your kidney works really well. Your doctor should check your kidney function before starting treatment.
  • Savaysa (edoxaban) cannot be used in people with mechanical heart valves or valvular atrial fibrillation.
  • There is no antidote for Savaysa (edoxaban).
ADVERTISEMENT
Used for
  • Prevention of stroke and blood clots in nonvalvular atrial fibrillation
  • Treatment of major blood clots (deep vein thrombosis and pulmonary embolism)
Dosage forms
  • Pill
  • Pill
Price
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
22 reviews so far
45%
saidit'sworth it
45%
saiditworked well
9%
saidit'sa big hassle

Have you used Xarelto (rivaroxaban)?

Leave a review
Not enough review data.Leave a review
Side effects
2possible side effects
  • Major bleeding needing transfusion
    4%
  • Bleeding in the stomach & intestines
    2%
See more detailed side effects
2possible side effects
  • Major bleeding
    7%
  • Bleeding of the stomach
    4%
See more detailed side effects
Risks and risk factors
  • Blood clots and stroke
    • Stopping Xarelto (rivaroxaban) too soon
    • Artificial heart valve
  • Blood clot in the spine
    • Spinal puncture (spinal tap)
    • Getting anesthesia in the spine (epidural anesthesia)
  • Unusual bleeding
    • History of bleeding problems
    • Severe high blood pressure
    • Age 65 or older
    • Drug interactions
    • Taking NSAIDs, aspirin, or other blood-thinning medicines
  • Increased side effects
    • Current kidney problems
    • Current liver problems
See more detailed risks and warnings
  • Not enough medicine in your blood
    • Excellent kidney function (filtration rate more than 95 mL/min
  • Blood clots and stroke
    • Stopping Savaysa (edoxaban) too early
    • Mechanical heart valve
    • Narrow mitral valve in the heart
  • Blood clot in the spine
    • Spinal puncture (spinal tap)
    • Getting anesthesia in the spine (epidural anesthesia)
  • Unusual bleeding
    • History of bleeding problems
    • Severe high blood pressure
    • Age 65 or older
    • Taking anti-inflammatory medicines like aspirin and ibuprofen
    • Taking other blood-thinning medicines
  • Increased side effects
    • Current kidney problems
    • Current liver problems
See more detailed risks and warnings