Compare Xopenex vs. Breo Ellipta

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Makes it easier to breathe if you have asthma, bronchitis, or emphysema.

Xopenex (levalbuterol) inhaler is very effective at relieving acute asthma attakcs in more moderate to severe airway conditions, but is more expensive.

Provides long-term control of symptoms related to asthma or COPD.

DRUG NAME combines two effective medicines for treatment of asthma or COPD into one easy to use daily inhaler, but doesn't work fast enough to relieve sudden breathing problems.

  • Xopenex (levalbuterol) works within minutes to help you breathe easier when you have breathing difficulty or an attack, especially in more severe conditions.
  • The inhaler can be used in children as young as 4 years old while the nebulizer solution can be used in children 6 years and older.
  • Xopenex (levalbuterol) may have less side effects such as rapid heartbeat than albuterol.
  • It is available as a generic.
  • The nebulizer solution is a good option for children and adults who have difficulty using a handheld inhaler.
  • Provides long-term control of symptoms unlike rescue inhalers.
  • Some may find this type of dry powder inhaler easier to use than a metered dose inhaler.
  • Combines two effective medications into one easy to use daily inhaler.
  • Xopenex (levalbuterol) is only relieves immediate symptoms and doesn't work to prevent future attacks, unlike maintenance medicines.
  • May not be the best option if you have a history of seizures, heart problems, thyroid problems or diabetes.
  • Xopenex (levalbuterol) is similar to albuterol, but it can be more expensive, especially the nebulizer solution.
  • Children might find the inhaler and nebulizer difficult to use. Parents or adults may need to help children use this medicine.
  • Unlike albuterol, Xopenex (levalbuterol) nebulizer solution cannot be mixed with other nebulized medicines.
  • Breo Ellipta (fluticasone / vilanterol) contains an ingredient, which may cause yeast to grow in your mouth and throat.
  • Not appropriate for those allergic to milk since it contains milk protein.
  • Other types of combination inhaler for COPD may work better to reduce the frequency of COPD attacks.
Used for
  • Chronic obstructive pulmonary disease (COPD)
  • Asthma
Dosage forms
  • Inhaler
  • Nebulizer solution
  • Inhaler
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Side effects
7possible side effects
  • Vomiting
  • Asthma symptoms
  • Accidental injury
  • Sore throat
  • Stuffy nose
  • Dizziness
  • Bronchitis
See more detailed side effects
5possible side effects
  • Nose and throat inflammation
  • Headache
  • Yeast infection in the mouth and throat (thrush)
  • Mouth and throat pain
  • Hoarse voice
See more detailed side effects
Risks and risk factors
  • Sudden lung spasms
    • First use of a new vial
  • Heart problems
    • History of heart problems
    • High blood pressure
  • Increased side effects
  • Worsening of asthma
  • Allergic reactions
  • Low potassium levels
    • Medicines that lower potassium levels
    • Taking certain diuretics
See more detailed risks and warnings
  • Asthma-related death
    • Children age 18 years or younger
  • Sudden breathing problems or worsening signs of COPD
  • Yeast infection of the mouth and throat
    • Not rinsing mouth after use
    • Using higher dose of Breo Ellipta (fluticasone / vilanterol)
  • Heart effects
    • Preexisting heart conditions
    • Arrhythmia
    • High blood pressure
  • Serious allergic reaction
    • Milk protein allergy
See more detailed risks and warnings