Compare Zantac vs. Pepto-Bismol
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Zantac 75 (ranitidine) is an effective and inexpensive medicine for hearburn with few side effects, but may interfere with other drugs.
Pepto-Bismol (bismuth subsalicylate) can help for many stomach and intestinal problems, but may take longer to work compared to some other anti-diarrheal medicines.
- Zantac 75 (ranitidine) works well to relieve heartburn symtoms and is quite tolerable.
- You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
- If you have trouble swallowing pills you may find the liquid product a good option.
- Inexpensive with over-the-counter and generic options.
- Coupons are available for the brand product - speak to your doctor or pharmacist.
- Pepto-Bismol (bismuth subsalicylate) works well to alleviate stomach and intestinal problems and doesn't have many side effects.
- Comes in easy to take chewable pills or liquid, if you do not like swallowing pills.
- Is inexpensive and available over the counter.
- Coupons are available. Speak to your doctor or pharmacist.
- Zantac 75 (ranitidine) doesn't work as quickly as some other acid reducers. Speak to your doctor or pharmacist if you need quicker relief.
- Zantac 75 (ranitidine) does not last as long as some other acid reducers. Speak to your doctor or pharmacist if you need longer relief.
- May not be as effective in healing the esophagus when it is inflammed or torn, known as erosive esophagitis. Your doctor will assess which medication is best for you.
- Can lower your vitamin B12 levels if you use Zantac 75 (ranitidine) for a long time. Your doctor can order lab tests to monitor your vitamin B12 levels.
- May not be as strong as other anti-diarrheal or antacid medications.
- Should not be used for more than 2 days if your diarrhea does not go away or if you have a fever.
- For symptoms other than diarrhea, should not be used for more than 7 days without your doctor's approval. Speak to your doctor if symptoms persist.
- Oral solution
- Oral syrup
- Chewable tablet
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- Aged 60 years or older
- Kidney conditions
- Liver conditions
- Drug interactions
- Acute porphyria
- Acute Porphyria
- Chronic lung problems
- Lung problems
- Reye's syndrome
- Children or teenagers that have or are recovering from flu/flu-like symptoms or chickenpox
- Allergy to salicylates
- Aspirin allergy
- NSAID allergy
- Hearing problems
- Age 60 or older
- Drug Interactions
- Aspirin-containing medications