Compare Zestoretic vs. Catapres
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lowers blood pressure.
Lisinopril/hydrochlorothiazide is a good 2-in-1 blood pressure-lowering medicine that protects kidney function.
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3.4/ 5 average rating with 294 reviewsforZestoretic
Lowers blood pressure.
Catapres (Clonidine) is a good addition if you need more than one medicine to control your blood pressure, but it has a lot of side effects. You can't miss doses.
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3.2/ 5 average rating with 78 reviewsforCatapres
Upsides
- Combination medicine for people with high blood pressure. Doctors might prescribe it when you need more than one medicine to control your blood pressure.
- The two drugs in Lisinopril/hydrochlorothiazide work together to lower blood pressure, remove extra water from your body, and lower your risk of heart attack and stroke.
- Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
- Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
- Can be added to other blood pressure-lowering medicines if you need additional blood pressure control.
- Available in a weekly patch for people that aren't good at taking medicine by mouth.
- Works in the brain, so it can help treat some nervous system and psychiatric conditions.
- Under the brand name Kapvay, it's used to treat ADHD in children and teenagers.
Downsides
- Comes in fixed dosage strengths, so it's harder for your doctor to adjust your dose.
- Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
- Makes you urinate more often.
- Doesn't work as well in people with severe kidney problems.
- Requires a yearly blood test to see how the medicine is affecting your body.
- Not safe to use if you're pregnant.
- Has a lot of side effects compared to other blood pressure-lowering medicine because it works in the brain.
- The pill form can make some people sleepy, dizzy, and have dry mouth.
- You can't miss doses. Stopping Clonidine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Used for
Dosage forms
- Pill
- Pill
- Extended release
- Patch
Price
Lowest price
$4.00
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$7.00
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Reviews
294 reviews so far
51%
saidit'sworth it
40%
saiditworked well
17%
saidit'sa big hassle
Have you used Zestoretic (Lisinopril / Hydrochlorothiazide)?
Leave a review78 reviews so far
42%
saidit'sworth it
33%
saiditworked well
35%
saidit'sa big hassle
Have you used Catapres (Clonidine)?
Leave a reviewSide effects
11possible side effects
- Dizziness8%
- Headache5%
- Cough4%
- Fatigue4%
- Orthostatic Effects3%
- Diarrhea3%
- Nausea2%
- Upper Respiratory Infection2%
- Muscle Cramps2%
- Asthenia2%
- Paresthesia2%
17possible side effects
- Erythema / pruritis26%
- Dry mouth25%
- Drowsiness12%
- Localized vesiculation7%
- Fatigue6%
- Headache5%
- Allergic contact sensitization5%
- Hyperpigmentation5%
- Lethargy3%
- Sedation3%
- Edema3%
- Excoriation3%
- Burning3%
- Insomnia2%
- Dizziness2%
- Impotence/sexual dysfunction2%
- Dry throat2%
Risks and risk factors
- Harm to fetus
- Women of childbearing age
- Unusual tongue swelling
- African descent
- Severe allergic reactions while on dialysis
- People requiring high flux dialysis
- Acute kidney failure
- History of kidney disease
- Heart problems due to high potassium
- Current kidney problems
- Medicine that increase potassium
- Use of salt substitute
- Cough
- Withdrawal
- Sudden discontinuation of medicine
- Driving impairment
- Taking with alcohol
- Taking other medicines that make you less alert
- Low heart rate (bradycardia)
- Age 65 years or older
- Using other medicine(s) that slows the heart