Compare Zetia vs. Antara

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Zetia (ezetimibe)

Prescription only

Antara (fenofibrate)

Prescription only
Lowers cholesterol.

Zetia (ezetimibe) can improve your cholesterol and can be used as an alternative to statins.

●●●●●
3.3/ 5 average rating with 128 reviewsforZetia
Lowers cholesterol and triglycerides.

Antara (fenofibrate) is effective at lowering triglyceride and cholesterol levels, but may cause liver problems and muscle pain.

●●●●●
2.5/ 5 average rating with 56 reviewsforAntara
Upsides
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Can be used with other medicines to improve cholesterol.
  • Available in a combination pill with simvastatin.
  • Available as a generic.
  • Antara (fenofibrate) can reduce triglycerides by about 20-50%.
  • Although not as effective at lowering triglycerides, Antara (fenofibrate) can lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).
  • There is a less expensive generic version available.
  • You only need to take it once a day, with or without food.
Downsides
  • Doesn't lower triglycerides (fats).
  • Hasn't been shown to lower the risk of heart attacks or heart disease.
  • By itself, it isn't as effective as statins for improving cholesterol.
  • Not as effective as statins in lowering cholesterol levels. You shouldn't take Antara (fenofibrate) by itself to lower cholesterol.
  • Drinking large amounts of alcohol regularly while taking Antara (fenofibrate) can increase your risk of liver damage.
  • Tell your doctor if you have a history of gallbladder, liver or kidney disease. Antara (fenofibrate) might not be the best choice to lower your triglyceride levels.
  • Antara (fenofibrate) can interact with other medications such as warfarin, colchicine, and sulfonylureas.
  • Antara (fenofibrate) was not shown to reduce rates of death in people with type 2 diabetes.
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Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price
$12.22
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Lowest price
$7.26
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Reviews
128 reviews so far
42%
saidit'sworth it
34%
saiditworked well
21%
saidit'sa big hassle

Have you used Zetia (ezetimibe)?

Leave a review
56 reviews so far
27%
saidit'sworth it
14%
saiditworked well
29%
saidit'sa big hassle

Have you used Antara (fenofibrate)?

Leave a review
Side effects
12possible side effects
  • Diarrhea
    4%
  • Common cold
    4%
  • Sore throat
    4%
  • Sinus infection
    3%
  • Joint pain
    3%
  • Pain in arms and legs
    3%
  • Muscle pain
    3%
  • Abnormal liver tests
    3%
  • Fatigue
    2%
  • Flu
    2%
  • Back pain
    2%
  • Gallbladder removal
    2%
See more detailed side effects
11possible side effects
  • Abnormal liver function tests
    8%
  • Respiratory disorder
    6%
  • Stomach pain
    5%
  • Back pain
    3%
  • Headache
    3%
  • Increased AST
    3%
  • Increased ALT
    3%
  • Increased creatine phosphokinase
    3%
  • Nausea
    2%
  • Constipation
    2%
  • Hay fever
    2%
See more detailed side effects
Risks and risk factors
  • Harm to fetus
  • Muscle pain
    • Taking Zetia (ezetimibe) with statins
  • Abnormal liver blood tests
    • Past history of liver disease
    • Taking Zetia (ezetimibe) with statins
See more detailed risks and warnings
  • Muscle pain
    • Taking Antara (fenofibrate) with statins
    • Elderly patients
    • Patients with diabetes
    • Patients with a history of renal failure.
  • Liver damage
    • History of liver disease
  • Gallstones
    • History of gallstones
  • Increased bleeding risk
    • Taking Antara (fenofibrate) with anticoagulants
  • Inflammation of pancreas
  • Changes in blood tests
See more detailed risks and warnings
Learn more about Zetia (ezetimibe)
Learn more about Antara (fenofibrate)