Compare Zetia vs. Vytorin
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lowers cholesterol.
Zetia (ezetimibe) can improve your cholesterol and can be used as an alternative to statins.
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3.3/ 5 average rating with 128 reviewsforZetia
Lowers cholesterol.
Vytorin is expensive and is no more effective than simvastatin by itself.
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3.3/ 5 average rating with 99 reviewsforVytorin
Upsides
- Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
- Can be used with other medicines to improve cholesterol.
- Available in a combination pill with simvastatin.
- Available as a generic.
- A 2-in-1 cholesterol-lowering combination medicine.
- Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
Downsides
- Doesn't lower triglycerides (fats).
- Hasn't been shown to lower the risk of heart attacks or heart disease.
- By itself, it isn't as effective as statins for improving cholesterol.
- In clinical studies, simvastatin/ezetimibe hasn't controlled cholesterol better than simvastatin alone.
- There's no generic available, so it can be expensive.
Used for
Dosage forms
- Pill
- Pill
Price
Lowest price
$9.26
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$68.60
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Reviews
128 reviews so far
42%
saidit'sworth it
34%
saiditworked well
21%
saidit'sa big hassle
Have you used Zetia (ezetimibe)?
Leave a review99 reviews so far
53%
saidit'sworth it
36%
saiditworked well
19%
saidit'sa big hassle
Have you used Vytorin (Ezetimibe / Simvastatin)?
Leave a reviewSide effects
12possible side effects
- Diarrhea4%
- Common cold4%
- Sore throat4%
- Sinus infection3%
- Joint pain3%
- Pain in arms and legs3%
- Muscle pain3%
- Abnormal liver tests3%
- Fatigue2%
- Flu2%
- Back pain2%
- Gallbladder removal2%
8possible side effects
- Headache6%
- Any side effect5%
- Increased ALT4%
- Myalgia4%
- Upper respiratory tract infection4%
- Diarrhea3%
- Influenza2%
- Pain in extremity2%
Risks and risk factors
- Harm to fetus
- Muscle pain
- Taking Zetia (ezetimibe) with statins
- Abnormal liver blood tests
- Past history of liver disease
- Taking Zetia (ezetimibe) with statins
- Muscle pain
- Asian patients taking high-dose niacin
- Liver damage
- Past history of liver disease
- heavy alcohol use
- High blood sugar
- Diabetes
- Increased risk for colds and flu
- Skin reactions
- Harm to fetus
- Pregnancy