Compare Ziagen vs. Epzicom

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Works with other medicines to treat HIV infection.

Ziagen (abacavir) is a first-choice medication that is used with others to treat HIV. It's important that your doctor test you for allergic reactions to Ziagen (abacavir) before starting the medication.

Works with other medicines to treat HIV infection.

Epzicom (abacavir / lamivudine) contains two medicines in one tablet, used with other medicines, to treat HIV infection. Your doctor does need to test you before you start it to make sure you don't get an allergic reaction.

Upsides
  • Ziagen (abacavir) is found in many other combination tablets.
  • Ziagen (abacavir) has few drug interactions.
  • People whose kidneys are not working as well can still take Ziagen (abacavir) without having to change its dose.
  • Kids 3 months and older can use Ziagen (abacavir).
  • Epzicom (abacavir / lamivudine) contains two first choice medicines used in combination with other medicines to treat HIV infections.
  • Compared to other HIV medicines, Epzicom (abacavir / lamivudine) does not have as many drug interactions with other medicines.
  • Can be taken with or without food.
  • Epzicom (abacavir / lamivudine) can be taken by children weighng at least 55lbs (25kg) or more.
Downsides
  • Ziagen (abacavir) can increase your risk of heart attack.
  • This is not a great medication to take if you have liver problems.
  • Severe allergic reactions have happened in some patients taking Ziagen (abacavir). Your doctor will test you for any possible risk of reaction before starting Ziagen (abacavir).
  • Epzicom (abacavir / lamivudine) isn't recommended if you'll need to adjust the dose of medications due to problems like kidney and/or liver damage.
  • Epzicom (abacavir / lamivudine) can increase your risk of heart attack, especially if you have other heart-related issues such as high blood pressure, high cholesterol, diabetes, or if you smoke.
  • Severe allergic reactions have happened in some patients taking Epzicom (abacavir / lamivudine). Your doctor will test you for any possible risk of reaction before starting Epzicom (abacavir / lamivudine).
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Dosage forms
  • Pill
  • Liquid
  • Pill
Price
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Reviews
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Side effects
21possible side effects
  • Nausea
    19%
  • Headache
    13%
  • Fatigue and discomfort
    12%
  • Dreams/sleep disorders
    10%
  • Nausea and vomiting
    10%
  • Severe allergic reactions
    9%
  • Fever and/or chills
    9%
  • Headaches/migraine
    7%
  • Diarrhea
    7%
  • Skin rashes
    7%
  • Rashes
    6%
  • Stomach pain
    6%
  • Depression
    6%
  • Dizziness
    6%
  • Muscle and joint pain
    6%
  • Ear/nose/throat infections
    5%
  • Viral respiratory infections
    5%
  • Anxiety
    5%
  • Bronchitis
    4%
  • Pneumonia
    4%
  • Vomiting
    2%
See more detailed side effects
13possible side effects
  • Severe allergic reaction
    9%
  • Insomnia
    7%
  • Depression/Depressed mood
    7%
  • Headache/Migraine
    7%
  • Fatigue/Malaise
    6%
  • Dizziness/Vertigo
    6%
  • Nausea
    5%
  • Diarrhea
    5%
  • Rash
    5%
  • Fever
    5%
  • Abdominal pain & inflammation
    4%
  • Abnormal dreams
    4%
  • Anxiety
    3%
See more detailed side effects
Risks and risk factors
  • Severe allergic reactions
    • Positive genetic test (HLA B5701)
  • Lactic acidosis & severe liver damage
    • Obesity
    • Women
    • History of liver problems
  • Immune system reactivation
  • Fat redistribution
  • Heart attack
    • High blood pressure
    • High cholesterol
    • Diabetes
See more detailed risks and warnings
  • Severe allergic reaction
    • Previous allergic reaction to Triumeq or abacavir
    • Presence of HLA-B*5701 gene
  • Lactic acidosis and Fatty liver
    • Liver disease
    • Women
    • Obesity
  • Acute exacerbation of hepatitis B virus (HBV)
    • Hepatitis B virus
  • Fat redistribution
    • HIV treatment
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
  • Heart attack
    • History of coronary heart disease
    • High blood pressure
    • Dyslipidemia
    • Diabetes mellitus
    • Smoking
See more detailed risks and warnings