Compare Zioptan vs. Betoptic

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lowers eye pressure and controls glaucoma.

Zioptan (tafluprost) is often a first choice treatment for lowering eye pressure to prevent and treat glaucoma, but is preservative-free so it has special storage instructions.

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  • Easy to use, with single-use containers and one drop daily in the evening.
  • Can use with other eye drops, if needed for better results.
  • Zioptan (tafluprost) is the only medicine in its class without preservatives, which may be less irritating to the eye.
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  • Zioptan (tafluprost) can permanently change your eyes and eyelids to brown, even after you stop using it.
  • Zioptan (tafluprost) may darken and increase the length, thickness and number of eyelashes, irritating the eyes.
  • No generic available, so can be expensive.
  • Is preservative-free so it should only be used 30 days after opening.
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Used for
  • Hypertension
  • Ocular hypertension
  • Primary open angle glaucoma
  • Angina pectoris - chronic
  • Cardiac dysrythmia
Dosage forms
  • Eye drops
  • Pill
  • Eye drops
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Side effects
4possible side effects
  • Heache
  • Common cold
  • Cough
  • Blurry vision
See more detailed side effects
The Betoptic S (Betaxolol) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Darkening of the eyes
    • Long term use
  • Darkening of lashes
    • Long term use
  • Darkening of contact lenses
    • (Re)inserting contact lenses too soon after applying Zioptan (tafluprost)
  • Eye injury/infection
    • Sharing eye drops with others
See more detailed risks and warnings
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