Compare Zofran vs. scopolamine
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Zofran (Ondansetron) works well to prevent nausea and vomiting, and it's available in different forms that you don't have to swallow.
Transderm-Scop (scopolamine) is a low-hassle patch that works well to prevent nausea and vomiting, but it takes several hours to work.
- Available in generic.
- Available in forms that you don't have to swallow (like a tablet or film that dissolves in your mouth) if you're having trouble keeping anything down.
- Starts working fast (in 30 minutes.
- Transderm-Scop (scopolamine) is well tolerated.
- Prevents nausea for 3 days.
- Because Transderm-Scop (scopolamine) is a skin patch, it's a good alternative to stopping nausea and vomiting if you're not able to swallow pills.
- Can cause headaches.
- Can interact with antidepressants.
- Can only be used to prevent nausea and vomiting, not to treat if it's already happening.
- Can only be used for prevention of nausea and vomiting. It can't stop nausea or vomiting that's already happening.
- The side effects can be worse if you are 65 and older.
- You might feel sleepy, drowsy, or have blurry vision while taking Transderm-Scop (scopolamine). Taking alcohol or other medicines that make you drowsy can make this effect worse.
- You're more likely to have heat stroke or feel dehydrated.
- It takes a few hours for Transderm-Scop (scopolamine) to kick in, so you have to remember to take it beforehand.
- Dissolving tablet
- Sublingual film
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- Increased AST and ALT5%
- Serotonin syndrome
- Heart rhythm problems
- Long QT syndrome
- Increased pressure in the eyes
- Open angle glaucoma
- Worsening stomach, bowel, or bladder blockages
- Blockages in the stomach, bowels or bladder
- Skin burns
- MRI examination
- Heat stroke
- Worsening seizures or psychosis
- History of seizures
- History of psychosis
- Sleepiness and dizziness
- Taking with alcohol
- Taking other medicines that make you less alert