Compare Zonegran vs. Aptiom
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Controls partial seizures.
Zonegran (zonisamide) is used with other medicines to help control partial seizures. It can't be used by itself.
Aptiom (eslicarbazepine) treats epilepsy, but is more expensive than other medicines that work like it.
- Available in generic.
- Can be given once a day, so it's easier to remember.
- You can take Zonegran (zonisamide) with or without food.
- Can be combined with other anti-seizure medicines if it doesn't work well enough by itself.
- Some people may tolerate Aptiom (eslicarbazepine) better than other medicines that work just like it.
- Zonegran (zonisamide) has to be used with other medicines to help control your seizures. It's not used by itself.
- Zonegran (zonisamide) is only approved in people age 16 or older.
- Zonegran (zonisamide) can cause kidney stones; so you have to make sure you drink plenty of liquids.
- Zonegran (zonisamide) can weaken your bones. Talk to your doctor about how to keep your bones strong.
- Other medicines used to control seizures can interact with Zonegran (zonisamide), so your doctor might have to change the dosing of your medications.
- More expensive than other medicines that work like it.
- Researchers do not know if this medicine works and is safe for children and elderly people.
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34possible side effects
- Loss of appetite13%
- Agitation or Irritability9%
- Stomach pain6%
- Difficulty controlling movements6%
- Difficulty with concentration6%
- Difficulty with memory6%
- Trouble sleeping6%
- Double vision6%
- Speech difficulties5%
- Difficulty controlling eye movements4%
- Prickling and tingling sensation4%
- Mental slowing4%
- Upset stomach3%
- Weight loss3%
- Skin rash3%
- Dry mouth2%
- Schizophrenia-like behavior2%
- Difficulties in verbal expression2%
- Stuffy nose2%
- Changes in taste2%
25possible side effects
- Double vision9%
- Blurry vision6%
- Inability to control your movements4%
- Loss of balance3%
- Dizziness or spinning sensation2%
- Other vision problems2%
- Abdominal pain2%
- Inflammation of stomach2%
- Lack of energy2%
- Problems with walking2%
- Swelling of the hands and feet2%
- Urinary tract infections2%
- Low sodium levels2%
Risks and risk factors
- Sulfa medicine allergy
- Allergy to sulfonamides such as Septra or Bactrim
- Lower blood cell counts
- Heat stroke and less sweating
- Under age 18
- Suicidal behavior
- Taking other medicines to control seizures
- Higher blood acid
- Kidney disease
- Severe COPD or lung disease
- Withdrawal seizures
- Changes in mood and suicidal thoughts and behaviors
- Serious skin problems
- Serious allergic reactions
- Low sodium levels
- Changes in alertness
- Higher doses of Aptiom (eslicarbazepine)
- Risk of increased seizures