Compare Zyprexa vs. Aristada

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Helps control your thoughts and mood.

Zyprexa (olanzapine) is good for treating psychosis, mania, and agitation, but it's more likely to cause weight gain and sleepiness than other antipsychotics.

3.7/ 5 average rating with 68 reviewsforZyprexa
Helps control your thoughts.

Aristada (Aripiprazole lauroxil) is good for schizophrenia, but you'll need to see your doctor every 4-6 weeks to get the injection.

Upsides
  • Effective at relieving psychotic symptoms, manic episodes, and agitation in people with schizophrenia and bipolar disorder.
  • Less likely to cause heart problems than other antipsychotics.
  • Less likely to cause movement problems compared to older antipsychotics.
  • Only needs to be given once a month.
  • Helps some people with their thoughts.
  • Comes in different strengths.
  • There are patient assistance programs to can help lower the cost of the copay.
  • It is given 4-6 weeks compared to every 4 weeks for other similar medications.
Downsides
  • More likely to cause weight gain and increase cholesterol or blood sugar compared to other antipsychotics.
  • Might make you more sleepy than some antipsychotics.
  • Mild risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive movements you can't control.
  • You may need routine blood tests to check how the medicine is affecting your body..
  • Likely expensive because it is only available as a brand name medication.
  • There are cheaper alternatives that should be considered before Aristada (Aripiprazole lauroxil).
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Used for
Dosage forms
  • Pill
  • Dissolving tablet
  • Injection
  • Injection
Price
Lowest price
$2341.04
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Reviews
68 reviews so far
41%
saidit'sworth it
51%
saiditworked well
51%
saidit'sa big hassle

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Side effects
9possible side effects
  • Drowsiness
    48%
  • Weight gain
    28%
  • Increased appetite
    28%
  • Headache
    17%
  • Fatigue
    14%
  • Dizziness
    7%
  • Dry Mouth
    7%
  • Abdominal pain
    6%
  • Pain in extremity
    5%
See more detailed side effects
6possible side effects
  • Inability to sit still
    11%
  • Injection site pain
    3%
  • Headache
    3%
  • Increased weight
    2%
  • Muscle damage
    2%
  • Insomnia
    2%
See more detailed side effects
Risks and risk factors
  • Increased risk of death
    • Elderly patients with dementia
  • Blood disorders
  • Neuroleptic malignant syndrome
  • Heart problems
    • History of heart problems
    • Drug interactions
  • Shaking and restlessness
  • Higher blood sugar, high cholesterol, and weight gain
    • People with diabetes
    • People with high cholesterol
See more detailed risks and warnings
  • Increased risk of death
    • Elderly patients with dementia
  • Neuroleptic malignant syndrome
    • Patients taking antipsychotics
  • Increased blood sugar, cholesterol, and weight gain
    • People with diabetes
    • People with high cholesterol
  • Shaking and restlessness
    • Long-term use of atypical antipsychotics
  • Heat stroke
  • Falls
See more detailed risks and warnings