Compare Zyprexa vs. Reglan
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Helps control your thoughts and mood.
Zyprexa (olanzapine) is good for treating psychosis, mania, and agitation, but it's more likely to cause weight gain and sleepiness than other antipsychotics.
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3.7/ 5 average rating with 68 reviewsforZyprexa
Relieves nausea and vomiting.
Reglan (metoclopramide) can stimulate your gut and relieve nausea, but it can only be used for a short period of time due to avoid serious side-effects.
Upsides
- Effective at relieving psychotic symptoms, manic episodes, and agitation in people with schizophrenia and bipolar disorder.
- Less likely to cause heart problems than other antipsychotics.
- Less likely to cause movement problems compared to older antipsychotics.
- Especially useful for relieving nausea caused by cancer chemotherapy.
- Available in an affordable, generic version
- If tablets are hard for you to swallow, Reglan (metoclopramide) is also available in as an orally disintegrating tablet or liquid form.
Downsides
- More likely to cause weight gain and increase cholesterol or blood sugar compared to other antipsychotics.
- Might make you more sleepy than some antipsychotics.
- Mild risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive movements you can't control.
- You may need routine blood tests to check how the medicine is affecting your body..
- Use for more than 12 weeks can cause involuntary movements of the eyes, tongue, face, arm, or legs.
- May take a while to relieve nausea and vomiting caused by delayed gastric emptying.
- Not a good option if you have Parkinson's disease, history of seizures, or blockage in your gut.
- You may need a lower dose if you have kidney problems.
Used for
- Diabetic gastroparesis
- Gastroesophegeal reflux
- Prevention of nausea and vomiting associated with chemotherapy
- Prevention of postoperative nausea and vomiting
- Radiological exam
- Small bowel intubation
- Gastric bezoars
- Hiccups
- Acute migraine
- Treatment of nausea and vomiting in advanced cancer
- Prevention of radiation therapy-induced nausea and vomiting
Dosage forms
- Pill
- Dissolving tablet
- Injection
- Pill
- Dissolving tablet
- Liquid
- Injectable
Price
Lowest price
$480.63
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$4.90
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Reviews
68 reviews so far
41%
saidit'sworth it
51%
saiditworked well
51%
saidit'sa big hassle
Have you used Zyprexa (olanzapine)?
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Side effects
9possible side effects
- Drowsiness48%
- Weight gain28%
- Increased appetite28%
- Headache17%
- Fatigue14%
- Dizziness7%
- Dry Mouth7%
- Abdominal pain6%
- Pain in extremity5%
4possible side effects
- Restlessness10%
- Drowsiness10%
- Fatigue10%
- Lack of energy10%
Risks and risk factors
- Increased risk of death
- Elderly patients with dementia
- Blood disorders
- Neuroleptic malignant syndrome
- Heart problems
- History of heart problems
- Drug interactions
- Shaking and restlessness
- Higher blood sugar, high cholesterol, and weight gain
- People with diabetes
- People with high cholesterol
- Late, irreversible, involuntary movements (tardive dyskinesia)
- Elderly
- Women
- Diabetics
- Depression
- Depression
- Neuroleptic malignant syndrome
- Early, reversible involuntary movements (extrapyramidal side-effects)
- Younger than 30 years old
- High doses of Reglan (metoclopramide)
- Children and teens