Compare Zyprexa vs. Rexulti
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Helps control your thoughts and mood.
Zyprexa (olanzapine) is good for treating psychosis, mania, and agitation, but it's more likely to cause weight gain and sleepiness than other antipsychotics.
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3.7/ 5 average rating with 68 reviewsforZyprexa
Helps improve your mood and control your thoughts.
Rexulti (brexpiprazole) is an option for people with depression or schizophrenia but it can be more expensive than other medicines.
Upsides
- Effective at relieving psychotic symptoms, manic episodes, and agitation in people with schizophrenia and bipolar disorder.
- Less likely to cause heart problems than other antipsychotics.
- Less likely to cause movement problems compared to older antipsychotics.
- Rexulti (brexpiprazole) does not cause as much weight gain as other similar medications.
- Fewer side effects compared to other similar medications.
Downsides
- More likely to cause weight gain and increase cholesterol or blood sugar compared to other antipsychotics.
- Might make you more sleepy than some antipsychotics.
- Mild risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive movements you can't control.
- You may need routine blood tests to check how the medicine is affecting your body..
- Avaliable only as brand name and can be more expensive than other options. However, there may be programs to help with co-pays.
- Rexulti (brexpiprazole) can cause restlessness, especially when you take higher doses and after a long period of time.
- Can increase your cholesterol, blood sugar, and cause weight gain.
- Elderly patients with dementia should not take Rexulti (brexpiprazole).
Used for
Dosage forms
- Pill
- Dissolving tablet
- Injection
- Pill
Price
Lowest price
$463.82
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$1157.45
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Reviews
68 reviews so far
41%
saidit'sworth it
51%
saiditworked well
51%
saidit'sa big hassle
Have you used Zyprexa (olanzapine)?
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Side effects
9possible side effects
- Drowsiness48%
- Weight gain28%
- Increased appetite28%
- Headache17%
- Fatigue14%
- Dizziness7%
- Dry Mouth7%
- Abdominal pain6%
- Pain in extremity5%
13possible side effects
- Agitation9%
- Weight gain7%
- Headache7%
- Sleepiness5%
- Common cold4%
- Tremors4%
- Fatigue3%
- Increased appetite3%
- Dizziness3%
- Anxiety3%
- Restlessness3%
- Constipation2%
- Decreased cortisol2%
Risks and risk factors
- Increased risk of death
- Elderly patients with dementia
- Blood disorders
- Neuroleptic malignant syndrome
- Heart problems
- History of heart problems
- Drug interactions
- Shaking and restlessness
- Higher blood sugar, high cholesterol, and weight gain
- People with diabetes
- People with high cholesterol
- Increased risk of death
- Elderly patients with dementia
- Suicidal thoughts or behavior
- Under 24 years of age
- Neuroleptic malignant syndrome
- Difficulty controlling movements
- Women over age 65
- Higher blood sugar and cholesterol, and weight gain
- People with diabetes
- People with high cholesterol
- Risk of infection