Compare Zyrtec vs. Dimetapp Cold And Allergy

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats allergy symptoms.

Zyrtec (cetirizine) can help you with some allergy symptoms without making you very drowsy.

3.8/ 5 average rating with 1232 reviewsforZyrtec
Relieves congestion and allergy symptoms for kids.

Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine) is good for multiple nasal symptoms, but it can make you really drowsy.

3.4/ 5 average rating with 24 reviewsforDimetapp Cold And Allergy
Upsides
  • Zyrtec (cetirizine) works to treat sneezing and runny nose, and causes less sedation compared to Benadryl.
  • Works well to also treat hives and itchy skin.
  • Zyrtec (cetirizine) is available over the counter without a prescription. It comes as a tablet, liquid, and quick-dissolving tablet.
  • It can provide relief of allergy symptoms for both kids and adults.
  • Zyrtec (cetirizine) has few drug interactions with other medicines.
  • Most people don't get any side effects from Zyrtec (cetirizine).
  • Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine) is a combination medicine with a decongestant and an antihistamine that's helpful in treating nasal symptoms related to cold and allergy.
  • Brompheniramine (the antihistamine) is useful for itchy eyes, runny nose, or constant sneezing.
  • Phenylephrine (the decongestant) is good for relieving congestion.
Downsides
  • Although it works fast, Zyrtec (cetirizine)'s effectiveness wears off for some people over time.
  • Zyrtec (cetirizine) can make you a little more sleepy compared to Allegra or Claritin.
  • Some people find that other more sedating antihistamines, like Benadryl (diphenhydramine), are more effective for them than Zyrtec (cetirizine).
  • If you don't really need both of the medications in this combination, you'd be taking extra medicine and might have extra side effects for no reason.
  • Brompheniramine (the antihistamine) can cause dizziness, drowsiness, dry eyes/mouth, and constipation.
  • Phenylephrine (the decongestant) doesn't last as long as other oral decongestants like pseudoephedrine, but can cause jitteriness.
  • The two medications in this medicine can somewhat work against each other, with one making you sleepy and the other making you jittery.
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Used for
Dosage forms
  • Pill
  • Chewable tablet
  • Dissolving tablet
  • Liquid
  • Chewable tablet
  • Liquid
Price
No pricing information available
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Reviews
1232 reviews so far
76%
saidit'sworth it
47%
saiditworked well
7%
saidit'sa big hassle

Have you used Zyrtec (cetirizine)?

Leave a review
24 reviews so far
58%
saidit'sworth it
29%
saiditworked well
8%
saidit'sa big hassle

Have you used Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine)?

Leave a review
Side effects
The Zyrtec (cetirizine) FDA package insert doesn’t have numbers about how common side effects are.
The Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Increased side effects in the elderly
    • Age 65 or older
  • Impaired alertness
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • History of liver or kidney conditions
    • History of liver or kidney disease
See more detailed risks and warnings
  • Driving impairment
    • Taking with alcohol
    • Taking with other medicines that make you less alert
  • Harm to fetus
    • Women of childbearing age
  • High blood pressure
    • History of high blood pressure
    • Taking MAO inhibitors
  • Antihistamine side effects
    • Age 65 years or older
    • Glaucoma
    • Benign prostatic hypertrophy (BPH)
See more detailed risks and warnings