Aciphex

(rabeprazole)

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Treats heartburn and ulcers.

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Our bottom line

Aciphex (rabeprazole) is good for treating heartburn and ulcers, but should not be used long-term.

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Quick facts about Aciphex
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (rabeprazole)

Upsides

  • Aciphex (rabeprazole) works better than over-the-counter medications that have not relieved your acid reflux.
  • The delayed-release pill provides relief over 24 hours.
  • Aciphex (rabeprazole) can be taken with or without food.
  • The capsule can be safely used by children as young as 1 year old.
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What to expect from Aciphex, on one page

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Downsides

  • Using Aciphex (rabeprazole) for a long time can can weaken your bones or increase your risk for infectious diarrhea.
  • Lowers magnesium and vitamin B12 in your body so you may need to take supplements.
  • Aciphex (rabeprazole) interferes with how many medications work.
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What to expect from Aciphex, on one page

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How it works

Aciphex (rabeprazole) is a proton pump inhibitor, which lowers the amount of acid released in your stomach.

Quick facts about Aciphex
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (rabeprazole)

Used for

Dosage forms

  • Delayed release pill
Tried Aciphex? Write a review!

Prices and coupons

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What to expect when you take Aciphex (rabeprazole) for Acid reflux or stomach ulcers

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
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  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
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  • Possible side effects
  • Headache
  • Diarrhea
  • Nausea
  • Vomiting
  • Abdominal pain
  • Pain
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Side effect rates for Aciphex (rabeprazole)

From 111 clinical trials of Aciphex when taken for acid reflux or stomach ulcers
  • Headache
    10%10%
  • Diarrhea
    5%5%
  • Nausea
    5%5%
  • Vomiting
    4%4%
  • Abdominal pain
    4%4%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Aciphex.

Aciphex (rabeprazole)
Placebo

People taking Aciphex felt side effect more

People taking Aciphex felt side effect less

No difference

Risks and Warnings for Aciphex (rabeprazole)

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  • Heartburn and upset stomach can be warning signs of more serious stomach problems. Call your doctor if you have throat pain, chest pain, belly pain, difficulty swallowing, dark bloody stools, or bloody vomitting. These may be signs of a more serious health problem.

Common concerns from people taking Aciphex (rabeprazole)

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Price
  • Worth it
    Worked well
    Some hassle
    Reviewed rabeprazoleon 2/9/2018I will still try to take it, My insurance co. Healthnet has stopped paying for it completely. It is very expensive. Will try to get discounts or coupons.
    72
    Woman
    Two years or more
    Would rather not say
Interactions
  • May interfere with how some medicines work. Make sure your doctor or pharmacist are aware of all the medicines or supplements you take.
Food
  • Take the pill with or without food. Swallow the pill whole. Do not chew, crush, or split.
  • Aciphex (rabeprazole) can be taken with or without food.