Afinitor

(everolimus)

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Treats different types of cancer.

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Our bottom line

Treats different types of cancer, but can cause uncomfortable side effects.

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Quick facts about Afinitor
  • Drug class: Cancer
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Afinitor (everolimus) comes as a pill rather than an injection, unlike some other cancer drugs.
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What to expect from Afinitor, on one page

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Downsides

  • Afinitor (everolimus) has many uncomfortable and potentially intolerable side effects.
  • You may be more prone to infections and take longer to recover from a wound while taking Afinitor (everolimus).
  • Some prescription medications, vitamins and supplements can interfere with how Afinitor (everolimus) works.
  • Afinitor (everolimus) might not be the best option if you have liver problems.
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What to expect from Afinitor, on one page

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How it works

Afinitor (everolimus) is a mechanistic target of rapamycin (mTOR) inhibitor. It inhibits cancer cell growth and multiplication.

Quick facts about Afinitor
  • Drug class: Cancer
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

Dosage forms

  • Pill
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Prices and coupons

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What to expect when you take Afinitor (everolimus) for Renal angiomyolipoma

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  • First few hoursHours
    First few daysDays
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  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Mouth sores
  • Vomiting
  • Diarrhea
  • Swelling in the limbs
  • Cough
  • Acne
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Side effect rates for Afinitor (everolimus)

From 407 clinical trials of Afinitor when taken for advanced pancreatic neuroendocrine tumors (pnet)
  • Mouth sores
    70%70%
    20%20%
  • Rash
    59%59%
    19%19%
  • Diarrhea
    50%50%
    25%25%
  • Tiredness
    45%45%
    27%27%
  • Swelling
    39%39%
    12%12%
  • Stomach pain
    36%36%
    32%32%
  • Nausea
    32%32%
    33%33%
  • Fever
    31%31%
    13%13%
  • Decreased appetite
    30%30%
    18%18%
  • Headache
    30%30%
    15%15%
  • Vomiting
    28%28%
    21%21%
  • Weight loss
    28%28%
    11%11%
  • Common cold
    25%25%
    13%13%
  • Cough
    25%25%
    13%13%
  • Nosebleed
    22%22%
    1%1%
  • Nail disorder
    22%22%
    2%2%
  • Itchy skin
    21%21%
    13%13%
  • Difficulty breathing
    20%20%
    7%7%
  • Weakness
    19%19%
    20%20%
  • Decreased taste sensitivity
    19%19%
    5%5%
  • Lung inflammation
    17%17%
  • Urinary tract infection
    16%16%
    6%6%
  • Joint pain
    15%15%
    7%7%
  • Back pain
    15%15%
    11%11%
  • Constipation
    14%14%
    13%13%
  • Pain in extremity
    14%14%
    6%6%
  • Difficulty sleeping
    14%14%
    8%8%
  • Dry skin
    13%13%
    6%6%
  • High blood pressure
    13%13%
    6%6%
  • Dizziness
    12%12%
    7%7%
  • Dry mouth
    11%11%
    4%4%
  • Throat pain
    11%11%
    6%6%
  • Diabetes
    10%10%
    5%5%
  • Muscle spasms
    10%10%
    4%4%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Afinitor.

Afinitor (everolimus)
Placebo

People taking Afinitor felt side effect more

People taking Afinitor felt side effect less

No difference

Risks and Warnings for Afinitor (everolimus)

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  • Afinitor (everolimus) is a medication that lowers the activity of your immune system, making you more prone to getting an infection. Make sure you wash your hands frequently, and stay away from sick people and crowds. If you notice a fever, cough, or any other symptoms of illness, let your doctor know immediately.

Common concerns from people taking Afinitor (everolimus)

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Kidneys and liver
  • Afinitor (everolimus) can cause kidney damage. The damage can be more pronounced when Afinitor (everolimus) is used with other medications that also cause kidney problems. Check with your doctor or pharmacist before starting any new prescription medications, vitamins or supplements. Contact your doctor immediately if you notice a reduced amount of urine, or swelling of your legs, ankles, or feet.