Bupap

(butalbital / acetaminophen)

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Treats tension or muscle contraction headaches.

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Our bottom line

Bupap (butalbital / acetaminophen) works well for tension or muscle contraction headaches, but isn’t the best option as it can be addictive.

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Quick facts about Bupap
  • Drug class: Pain
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (butalbital / acetaminophen)

Upsides

  • Bupap (butalbital / acetaminophen) works quickly to reduce stressed-induced headaches.
  • Bupap (butalbital / acetaminophen) is available in a cheaper, generic version.
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What to expect from Bupap, on one page

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Downsides

  • Bupap (butalbital / acetaminophen) is not a good medication for long-term use because it can cause dangerous withdrawal symptoms, intoxication, and dependence.
  • Not recommended for use by elderly patients due to risk of dependence and overdose.
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What to expect from Bupap, on one page

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How it works

Bupap (butalbital / acetaminophen) is a combination of two medications. Butalbital is a barbiturate that relaxes you by acting on the central nervous system, and acetaminophen relieves pain.

Quick facts about Bupap
  • Drug class: Pain
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (butalbital / acetaminophen)

Used for

Dosage forms

  • Pill
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Prices and coupons

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What to expect when you take Bupap (butalbital / acetaminophen) for Tension or muscle contraction headache

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  • First few hoursHours
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  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
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  • Possible side effects
  • Nausea
  • Vomiting
  • Stomach pain
  • Intoxicated feeling
  • Drowsiness
  • Lightheadedness
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Side effect rates for Bupap (butalbital / acetaminophen)

Risks and Warnings for Bupap (butalbital / acetaminophen)

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    • Higher risk if:
    • › Drinking more than 2 alcoholic beverages a day
    • › Taking Bupap (butalbital / acetaminophen) with other acetaminophen-containing medicines
    • › History of liver disease

    Bupap (butalbital / acetaminophen) contains acetaminophen (Tylenol). Taking too much acetaminophen can cause permanent and life-threatening liver damage. Using more than 4000 mg of acetaminophen can cause serious harm to your liver, so be sure not to take more than the recommended dose of Bupap (butalbital / acetaminophen) or other medications that contain acetaminophen.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Bupap (butalbital / acetaminophen)

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Sleep
  • Can make you sleepy. Be careful driving or doing other activities that require concentration until you know how Bupap (butalbital / acetaminophen) affects you.