Agrylin

(anagrelide)

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Lowers platelet count.

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Our bottom line

Agrylin (anagrelide) is effective at lowering platelet counts in certain cancers, which decreases risk of blood clots, heart attack, and stroke, but it should be used with caution in people with heart conditions.

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    $41.42
Quick facts about Agrylin
  • Drug class: Hematopoietic
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (anagrelide)

Upsides

  • Agrylin (anagrelide) is an effective treatment option for lowering platelet counts.
  • It is available as a cheaper, generic form.
  • Agrylin (anagrelide) can be used in patients with kidney problems.
  • It does not have to be injected. It is available as an oral capsule.
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What to expect from Agrylin, on one page

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Downsides

  • Agrylin (anagrelide) requires monitoring of the heart prior to initiating and periodically during treatment.
  • It should be avoided in patients with severe liver impairment.
  • You most likely will have to take Agrylin (anagrelide) more than once a day, especially at the start of treatment.
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What to expect from Agrylin, on one page

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How it works

Agrylin (anagrelide) is an antiplatelet medicine that lowers platelet counts by slowing the accelerated platelet development seen in some cancers.

Quick facts about Agrylin
  • Drug class: Hematopoietic
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (anagrelide)

Used for

  • Thrombocythemia

Dosage forms

  • Pill
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Prices and coupons

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What to expect when you take Agrylin (anagrelide) for Thrombocythemia

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Palpitations
  • Weakness
  • Swelling
  • Diarrhea
  • Headache
  • Nausea
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Side effect rates for Agrylin (anagrelide)

  • Headache
    44%44%
  • Palpitations
    26%26%
  • Diarrhea
    26%26%
  • Weakness
    23%23%
  • Swelling
    21%21%
  • Nausea
    17%17%
  • Stomach pain
    16%16%
  • Pain
    15%15%
  • Dizziness
    15%15%
  • Difficulty breathing
    12%12%
  • Vomiting
    10%10%
  • Bloating
    10%10%
  • Fever
    9%9%
  • Swelling in the peripheries
    9%9%
  • Increased heart rate
    8%8%
  • Chest pain
    8%8%
  • Decreased appetite
    8%8%
  • Rash
    8%8%
  • Malaise
    6%6%
  • Cough
    6%6%
  • Itchy skin
    6%6%
  • Back pain
    6%6%
  • Burning/prickling sensation
    6%6%
  • Indigestion
    5%5%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Agrylin.

Agrylin (anagrelide)
Placebo

People taking Agrylin felt side effect more

People taking Agrylin felt side effect less

No difference

Risks and Warnings for Agrylin (anagrelide)

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    • Higher risk if:
    • Taking Agrylin (anagrelide) with other medications that increase bleeding (ie. aspirin, anticoagulants, NSAIDs, antiplatelet agents, selective serotonin reuptake inhibitors).

    While taking Agrylin (anagrelide), you are at a higher risk of bleeding. Use of Agrylin (anagrelide) with aspirin can increase your risk of bleeding as well. Your doctor will likely assess your risks of bleeding before initiating treatment with this medication. You should monitor for signs and symptoms of bleeding, such as bruises, bleeding gums, dark, tarry stools and blood in your urine. Contact your doctor immediately if you notice these symptoms.

Common concerns from people taking Agrylin (anagrelide)

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Food
  • Agrylin (anagrelide) can be taken with or without food.
Kidneys and liver
  • Agrylin (anagrelide) can be used in patients with kidney problems.