Anzemet

(dolasetron)

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Helps prevent nausea and vomiting

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Our bottom line

Anzemet (dolasetron) prevents nausea and vomiting and does not have many side effects.

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Quick facts about Anzemet
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Reduced nausea and vomiting in people receiving chemotherapy.
  • Well-tolerated with mild headache as the most common side effect.
  • Requires only 1 dose prior to chemotherapy and once daily dosing after chemotherapy if needed for delayed nausea/vomiting.
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Downsides

  • Anzemet (dolasetron) doesn't treat nausea and vomiting that's already happening. It only works to prevent future episodes.
  • High doses of Anzemet (dolasetron) can cause problems with heart rhythm.
  • Can be expensive since a generic version is not available.
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What to expect from Anzemet, on one page

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How it works

Anzemet (dolasetron) is a 5-HT3 receptor antagonist. It prevents nausea and vomiting by blocking the nerves that activate a nausea and vomiting response.

Quick facts about Anzemet
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

Dosage forms

  • Pill
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Prices and coupons

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What to expect when you take Anzemet (dolasetron) for Nausea and vomiting from chemotherapy

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  • Effectiveness
  • Full effects
  • First few hoursHours
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  • Possible side effects
  • Headache
  • Fatigue
  • Diarrhea
  • Decreased heart rate
  • Dizziness
  • Indigestion
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Side effect rates for Anzemet (dolasetron)

From 227 clinical trials of Anzemet when taken for nausea and vomiting from chemotherapy (100 mg)
  • Headache
    23%23%
  • Fatigue
    6%6%
  • Diarrhea
    5%5%
  • Decreased heart rate
    4%4%
  • Dizziness
    3%3%
  • Pain
    3%3%
  • Increased heart rate
    3%3%
  • Indigestion
    2%2%
  • Chills/shivering
    2%2%
0%
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80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Anzemet.

Anzemet (dolasetron)
Placebo

People taking Anzemet felt side effect more

People taking Anzemet felt side effect less

No difference

Risks and Warnings for Anzemet (dolasetron)

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    • Higher risk if:
    • › History of heart rhythms such as long QT syndrome or atrial fibrillation
    • › Heart failure
    • › Taking other medications that can affect heart rhythms
    • › Low potassium or magnesium levels
    • › Advanced age

    Anzemet (dolasetron) can cause irregular heartbeats that may be life-threatening. Talk to your doctor about any history of heart rhythm irregularities. Call your doctor or get help help right away if you have a heartbeat that does not feel normal.