Apriso

(mesalamine)

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Maintains remission of ulcerative colitis

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Our bottom line

Apriso (mesalamine) is an effective medication for maintaining remission of ulcerative colitis that's generally well tolerated, but commonly causes headache.

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    $486.60
Quick facts about Apriso
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Apriso (mesalamine) is only available as a tablet, however, mesalamine is available in different forms, including tablets, capsules, enemas, and suppositories.
  • Certain forms of Apriso (mesalamine) can be used during pregnancy. Talk to your doctor if you're pregnant, or plan on becoming pregnant, and you have bowel inflammation.
  • It is a good option even if you have kidney or liver disease.
  • Since Apriso (mesalamine) is an extended release form, the pill is taken only once a day compared to other similar medicines and can be less irritating to the stomach and intestines.
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What to expect from Apriso, on one page

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Downsides

  • Although you only have to take it once in the morning, you may need to take 4 capsules.
  • Apriso (mesalamine) is not available as a cheaper, generic form.
  • Should only be used if you're 18 or older.
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What to expect from Apriso, on one page

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How it works

Apriso (mesalamine) is an anti-inflammatory medicine that lowers the body's natural inflammatory signals within your intestines, helping relieve your symptoms.

Quick facts about Apriso
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Dosage forms

  • Extended-release pill
Tried Apriso? Write a review!

Prices and coupons

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What to expect when you take Apriso (mesalamine) for Ulcerative colitis

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
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  • Possible side effects
  • Headache
  • Diarrhea
  • Upper stomach pain
  • Nausea
  • Common cold
  • Flu-like symptoms
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Side effect rates for Apriso (mesalamine)

From 552 clinical trials of Apriso when taken for ulcerative colitis
  • Headache
    11%11%
    8%8%
  • Diarrhea
    8%8%
    7%7%
  • Upper stomach pain
    5%5%
    3%3%
  • Nausea
    4%4%
    3%3%
  • Common cold
    4%4%
    3%3%
  • Flu-like symptoms
    4%4%
    4%4%
  • Sinus infection
    3%3%
    3%3%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Apriso.

Apriso (mesalamine)
Placebo

People taking Apriso felt side effect more

People taking Apriso felt side effect less

No difference

Risks and Warnings for Apriso (mesalamine)

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    • Higher risk if:
    • Preexisting liver problems
    • Taking other medications toxic to the liver

    Although very rare, Apriso (mesalamine) can cause injury to your liver, and lead to liver failure if not treated appropriately. Let your doctor know and get medical attention if you notice yellowing skin or eyes, dark urine, feel tired, or upset stomach or stomach pain.

Common concerns from people taking Apriso (mesalamine)

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Food
  • Take with or without food.
Kidneys and liver
  • Apriso (mesalamine) can cause kidney problems. Let you doctor know if you are unable to pass urine, notice a change in how much urine is passed, blood in the urine, or increased weight gain. Your doctor will likely check your kidney function before starting Apriso (mesalamine) and periodically throughout treatment with this medication.
  • It is a good option even if you have kidney or liver disease.