Lialda

(Mesalamine)

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Treats inflammatory bowel disease.

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Our bottom line

Lialda (Mesalamine) is an effective first-line medicine for inflammatory bowel disease. There isn't a generic version and you'll have to take it multiple times a day.

Lowest price near you
  • Price before coupon
    $788.49
  • Lowest price with coupon
    $388.89
    51% savings
Quick facts about Asacol
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (mesalamine)

Upsides

  • Effective first-line medication for treating and lowering the symptoms of mild inflammatory bowel disease.
  • About half the people who have mild to moderate colon inflammation and take Lialda (Mesalamine) will see improvement.
  • Available in tablets, capsules, enemas, and suppositories.
  • Certain forms of Lialda (Mesalamine) can be used during pregnancy. Talk to your doctor if you're pregnant, or plan on becoming pregnant, and you want to take Lialda (Mesalamine).
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Downsides

  • No generic versions are available for the tablets, capsules, and suppositories (meaning it could be somewhat expensive).
  • Doesn't work well for severe colon inflammation.
  • You may need to take Lialda (Mesalamine) three or four times a day.
  • Not a good option if you have kidney disease.
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How it works

Lialda (Mesalamine) is an anti-inflammatory medication. Researchers don't know exactly how Lialda (Mesalamine) works in the colon, but it seems to lower the chemicals in the body that cause inflammation.

Quick facts about Asacol
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (mesalamine)

Dosage forms

  • Pill
  • Extended release
  • Enema
  • Suppository
Tried Asacol? Write a review!

Prices and coupons

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What to expect when you take Lialda (Mesalamine) for Ulcerative colitis

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Headache
  • Nausea
  • Stuffy nose
  • Abdominal pain
  • Worsening of colitis
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Side effect rates for Lialda (Mesalamine)

From 239 clinical trials of Asacol when taken for ulcerative colitis
  • Headache
    35%35%
    36%36%
  • Abdominal pain
    18%18%
    14%14%
  • Eructation
    16%16%
    15%15%
  • Pain
    14%14%
    8%8%
  • Nausea
    13%13%
    15%15%
  • Pharyngitis
    11%11%
    9%9%
  • Dizziness
    8%8%
    8%8%
  • Asthenia
    7%7%
    15%15%
  • Diarrhea
    7%7%
    9%9%
  • Back pain
    7%7%
    5%5%
  • Fever
    6%6%
    8%8%
  • Rash
    6%6%
    3%3%
  • Dyspepsia
    6%6%
    1%1%
  • Rhinitis
    5%5%
    5%5%
  • Arthralgia
    5%5%
    3%3%
  • Hypertonia
    5%5%
    3%3%
  • Vomiting
    5%5%
    2%2%
  • Constipation
    5%5%
    1%1%
  • Flatulence
    3%3%
    7%7%
  • Dysmenorrhea
    3%3%
    3%3%
  • Chest pain
    3%3%
    2%2%
  • Chills
    3%3%
    2%2%
  • Flu syndrome
    3%3%
    2%2%
  • Peripheral edema
    3%3%
    2%2%
  • Myalgia
    3%3%
    1%1%
  • Sweating
    3%3%
    1%1%
  • Colitis exacerbation
    3%3%
  • Pruritus
    3%3%
  • Adverse events
    3%3%
    2%2%
  • Acne
    2%2%
    1%1%
  • Increased cough
    2%2%
    1%1%
  • Malaise
    2%2%
    1%1%
  • Arthritis
    2%2%
  • Conjunctivitis
    2%2%
  • Insomnia
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Asacol.

Lialda (Mesalamine)
Placebo

People taking Asacol felt side effect more

People taking Asacol felt side effect less

No difference

Risks and Warnings for Lialda (Mesalamine)

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    • Higher risk if:
    • Asthma
    • Rhinitis
    • Nasal polyps
    • Aspirin allergy
    • NSAID allergy

    Rarely, Lialda (Mesalamine) can cause serious allergic reactions. These reactions can make it difficult to breathe or cause a severe rash that can be life-threatening. Stop taking Lialda (Mesalamine) and report any skin rash, fever, swelling, or trouble breathing to a doctor right away.

Pharmacist Q&A

Lialda (Mesalamine) questions for

Frequently Asked Questions

This medication treats mildly to moderately active ulcerative colitis.

Who is this drug for?

This medication treats mildly to moderately active ulcerative colitis.

Common concerns from people taking Lialda (Mesalamine)

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Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for Asacol
CWeigh risks vs. benefits
Food
  • Not sure
    Some hassle
    Reviewed Asacolon 12/7/2016Best to take it all at once with your biggest meal of the day
    33
    Woman
    Ulcerative colitis (mild to moderate)
Kidneys and liver
  • Lialda (Mesalamine) is broken down by the kidney and liver. If you have kidney or liver problems, talk to your doctor because you may need to take a different dose of the medication.
  • Rarely, Lialda (Mesalamine) can cause liver injury, hepatitis, and liver failure. Let your doctor know and get medical attention if you notice yellowing skin or eyes.
  • Not a good option if you have kidney disease.