Bidil

(hydralazine / isosorbide dinitrate)

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Treats heart failure.

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Our bottom line

Adding Bidil (hydralazine / isosorbide dinitrate) to the treatment of heart failure reduces the workload on your heart. It works especially well in African Americans.

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    $297.96
Quick facts about Bidil
  • Drug class: Cardiovascular
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Bidil (hydralazine / isosorbide dinitrate) is the only heart failure medicine approved specifically for African Americans.
  • Bidil (hydralazine / isosorbide dinitrate) can help improve symptoms of heart failure and keep your heart healthier.
  • You only need to take one pill instead of the two medicines in Bidil (hydralazine / isosorbide dinitrate) separately.
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What to expect from Bidil, on one page

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Downsides

  • Headaches and dizziness are very common side effects of Bidil (hydralazine / isosorbide dinitrate). These side effects should lessen over time but let your doctor know if they do not.
  • Bidil (hydralazine / isosorbide dinitrate) is brand only and may be expensive. However, this combination medicine is available separately as generics.
  • The combination of two medicines can cause more side effects.
  • Bidil (hydralazine / isosorbide dinitrate) does not replace your other heart failure medications. It is taken together with them.
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What to expect from Bidil, on one page

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How it works

The two medicines in Bidil (hydralazine / isosorbide dinitrate) help your blood vessels relax and widen which helps your heart pump blood better.

Quick facts about Bidil
  • Drug class: Cardiovascular
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Dosage forms

  • Pill
Tried Bidil? Write a review!

Prices and coupons

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What to expect when you take Bidil (hydralazine / isosorbide dinitrate) for Heart failure

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Headache
  • Dizziness
  • Lack of energy
  • Fast heart rate
  • Low blood pressure
  • Prickling sensation
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Side effect rates for Bidil (hydralazine / isosorbide dinitrate)

From 1044 clinical trials of Bidil when taken for heart failure (20 mg/37.5 mg)
  • Headache
    50%50%
    21%21%
  • Dizziness
    32%32%
    14%14%
  • Lack of energy
    14%14%
    11%11%
  • Nausea
    10%10%
    6%6%
  • Low blood pressure
    8%8%
    4%4%
  • Sinus infection
    4%4%
    2%2%
  • Fast heart rate
    4%4%
    2%2%
  • Prickling sensation
    4%4%
    2%2%
  • Vomiting
    4%4%
    2%2%
  • Lazy eye
    3%3%
    1%1%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Bidil.

Bidil (hydralazine / isosorbide dinitrate)
Placebo

People taking Bidil felt side effect more

People taking Bidil felt side effect less

No difference

Risks and Warnings for Bidil (hydralazine / isosorbide dinitrate)

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  • Bidil (hydralazine / isosorbide dinitrate) can cause symptoms that look like systemic lupus erythematosus (SLE). Tell your doctor if you notice a rash on your cheeks or other body parts or have muscle or joint pain. This is more likely to happen with larger doses over a longer period of time. Symptoms usually go away if you stop taking it.