Butrans

(buprenorphine)

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Treats severe pain around the clock.

Skip Upsides & Downsides section. Skip to side effects section.
Prescription opioids are used to treat several kinds of pain - but they carry significant risks, including addiction. Learn more about these drugs and be sure to discuss the risks with your doctor.

Our bottom line

Butrans (buprenorphine) is effective for treating severe pain around-the-clock, but it has a high potential for abuse and misuse.

Lowest price near you
  • Price before coupon
    $336.14
  • Lowest price with coupon
    $86.90
    74% savings
Quick facts about Butrans
  • Drug class: Pain
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (buprenorphine)

Upsides

  • Butrans (buprenorphine) comes in a patch form and only needs to be changed once every 7 days.
  • Butrans (buprenorphine) works around-the-clock to help relieve pain.
  • The Butrans (buprenorphine) patch can be applied on up to 8 different areas of the body.
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What to expect from Butrans, on one page

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Downsides

  • Butrans (buprenorphine) takes about half a day to start kicking in.
  • Butrans (buprenorphine) has a high potential for misuse and abuse.
  • Butrans (buprenorphine) can cause life-threatening breathing problems, even when used at the correct dose.
  • Older people shouldn't take Butrans (buprenorphine) due to its effects on blood pressure.
  • Other pain relievers may be needed for breakthrough pain.
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What to expect from Butrans, on one page

Download Fact Sheet
How it works

Butrans (buprenorphine) is an opioid that provides pain relief by acting on specific receptors in your brain.

Quick facts about Butrans
  • Drug class: Pain
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (buprenorphine)

Used for

  • Pain management

Dosage forms

  • Patch
Tried Butrans? Write a review!

Prices and coupons

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What to expect when you take Butrans (buprenorphine) for Persistent moderate to severe pain

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Nausea
  • Application site itchiness
  • Dizziness
  • Headache
  • Sleepiness
  • Constipation
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Side effect rates for Butrans (buprenorphine)

From 653 clinical trials of Butrans when taken for persistent moderate to severe pain
  • Nausea
    21%21%
    6%6%
  • Application site itchiness
    15%15%
    12%12%
  • Dizziness
    15%15%
    7%7%
  • Headache
    14%14%
    9%9%
  • Sleepiness
    13%13%
    4%4%
  • Constipation
    13%13%
    5%5%
  • Vomiting
    9%9%
    1%1%
  • Application site redness
    7%7%
    2%2%
  • Application site rash
    6%6%
    6%6%
  • Dry mouth
    6%6%
    2%2%
  • Tiredness
    5%5%
    1%1%
  • Excessive sweating
    4%4%
    1%1%
  • Accumulation of fluid in arms and legs
    3%3%
    1%1%
  • Itching
    3%3%
  • Stomach discomfort
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Butrans.

Butrans (buprenorphine)
Placebo

People taking Butrans felt side effect more

People taking Butrans felt side effect less

No difference

Risks and Warnings for Butrans (buprenorphine)

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    • Higher risk if:
    • Personal or family history of substance abuse
    • History of mental illness

    Butrans (buprenorphine) has a high potential for abuse, misuse, or addiction, which can lead to complications such as overdose and death. A person can become addicted to it even at normal doses. Do not place Butrans (buprenorphine) in your mouth. Chewing or swallowing it might lead to a higher chance of choking and overdosing. Your doctor will determine if this is the right treatment option for you based on your history of drug use and medication taking habits.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Pharmacist Q&A

Butrans (buprenorphine) questions for

Frequently Asked Questions

This medication treats moderate to severe chronic pain.

Who is this drug for?

This medication treats moderate to severe chronic pain.

Common concerns from people taking Butrans (buprenorphine)

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Pain
  • Your doctor may have you continue to take oral pain relievers, while Butrans (buprenorphine) is kicking in. Do not stop Butrans (buprenorphine) until discussing with your doctor.
  • Other pain relievers may be needed for breakthrough pain.
  • Not worth it
    Big hassle
    Reviewed Butranson 10/12/2017Stay away from this. The withdrawal took 2 weeks of pain and sweating. Very uncomfortable.
    43
    Woman
    A few months
    Pain management
Sleep
  • Butrans (buprenorphine) should not be taken with certain medications used for sleep, anxiety, muscle relaxation, and other opioids since they can all build up drowsiness. In more severe cases, your breathing could be slowed down so much that it becomes life-threatening. Talk to your doctor before you start taking any other new medications.
  • Avoid drinking alcohol or taking other medicines that can cause drowsiness.